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Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy

We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall...

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Detalles Bibliográficos
Autores Principales: Caceres, Diego H., Scheel, Christina M., Tobón, Ángela M., Cleveland, Angela Ahlquist, Restrepo, Ángela, Brandt, Mary E., Chiller, Tom, Gómez, Beatriz L.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2014
Materias:
Amphotericin B deoxycholate
Fungus antigen
Histoplasma capsulatum antigen
Itraconazole
Unclassified drug
Acquired immune deficiency syndrome
Antigen detection
Article
Colombia
Enzyme linked immunosorbent assay
Follow up
Histoplasma capsulatum
Histoplasmosis
Human
Major clinical study
Nonhuman
Priority journal
Sensitivity and specificity
Treatment response
Urinalysis
Validation process
AIDS-Related Opportunistic Infections
Cohort analysis
Diagnostic procedure
Drug monitoring
Histoplasma
Immunology
Procedures
Prospective study
Urine
Validation study
Clinical Laboratory Techniques
Cohort Studies
Drug Monitoring
Enzyme-Linked Immunosorbent Assay
Humans
Prospective Studies
Sensitivity and Specificity
Fungal
Antigens
Acceso en línea:https://repository.urosario.edu.co/handle/10336/23675
https://doi.org/10.1128/CVI.00101-14

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