Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy

"We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the o...

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Autores Principales: Caceres, Diego H., Scheel, Christina M., Tobón, Ángela M., Cleveland, Angela Ahlquist, Restrepo, Ángela, Brandt, Mary E., Chiller, Tom, Gómez, Beatriz L.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2014
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/23675
https://doi.org/10.1128/CVI.00101-14
id ir-10336-23675
recordtype dspace
spelling ir-10336-236752021-01-21T08:30:13Z Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy Caceres, Diego H. Scheel, Christina M. Tobón, Ángela M. Cleveland, Angela Ahlquist Restrepo, Ángela Brandt, Mary E. Chiller, Tom Gómez, Beatriz L. Amphotericin B deoxycholate Fungus antigen Histoplasma capsulatum antigen Itraconazole Unclassified drug Fungus antigen Acquired immune deficiency syndrome Antigen detection Article Colombia Enzyme linked immunosorbent assay Follow up Histoplasma capsulatum Histoplasmosis Human Major clinical study Nonhuman Priority journal Sensitivity and specificity Treatment response Urinalysis Validation process AIDS-Related Opportunistic Infections Cohort analysis Diagnostic procedure Drug monitoring Enzyme linked immunosorbent assay Histoplasma Histoplasmosis Immunology Procedures Prospective study Urine Validation study AIDS-Related Opportunistic Infections Antigens, Fungal Clinical Laboratory Techniques Cohort Studies Colombia Drug Monitoring Enzyme-Linked Immunosorbent Assay Histoplasma Histoplasmosis Humans Prospective Studies Sensitivity and Specificity "We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy. Copyright © 2014, American Society for Microbiology. All Rights Reserved." 2014 2020-05-26T00:04:19Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 1556679X 15566811 https://repository.urosario.edu.co/handle/10336/23675 https://doi.org/10.1128/CVI.00101-14 eng info:eu-repo/semantics/openAccess application/pdf instname:Universidad del Rosario reponame:Repositorio Institucional EdocUR
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic Amphotericin B deoxycholate
Fungus antigen
Histoplasma capsulatum antigen
Itraconazole
Unclassified drug
Fungus antigen
Acquired immune deficiency syndrome
Antigen detection
Article
Colombia
Enzyme linked immunosorbent assay
Follow up
Histoplasma capsulatum
Histoplasmosis
Human
Major clinical study
Nonhuman
Priority journal
Sensitivity and specificity
Treatment response
Urinalysis
Validation process
AIDS-Related Opportunistic Infections
Cohort analysis
Diagnostic procedure
Drug monitoring
Enzyme linked immunosorbent assay
Histoplasma
Histoplasmosis
Immunology
Procedures
Prospective study
Urine
Validation study
AIDS-Related Opportunistic Infections
Antigens, Fungal
Clinical Laboratory Techniques
Cohort Studies
Colombia
Drug Monitoring
Enzyme-Linked Immunosorbent Assay
Histoplasma
Histoplasmosis
Humans
Prospective Studies
Sensitivity and Specificity
spellingShingle Amphotericin B deoxycholate
Fungus antigen
Histoplasma capsulatum antigen
Itraconazole
Unclassified drug
Fungus antigen
Acquired immune deficiency syndrome
Antigen detection
Article
Colombia
Enzyme linked immunosorbent assay
Follow up
Histoplasma capsulatum
Histoplasmosis
Human
Major clinical study
Nonhuman
Priority journal
Sensitivity and specificity
Treatment response
Urinalysis
Validation process
AIDS-Related Opportunistic Infections
Cohort analysis
Diagnostic procedure
Drug monitoring
Enzyme linked immunosorbent assay
Histoplasma
Histoplasmosis
Immunology
Procedures
Prospective study
Urine
Validation study
AIDS-Related Opportunistic Infections
Antigens, Fungal
Clinical Laboratory Techniques
Cohort Studies
Colombia
Drug Monitoring
Enzyme-Linked Immunosorbent Assay
Histoplasma
Histoplasmosis
Humans
Prospective Studies
Sensitivity and Specificity
Caceres, Diego H.
Scheel, Christina M.
Tobón, Ángela M.
Cleveland, Angela Ahlquist
Restrepo, Ángela
Brandt, Mary E.
Chiller, Tom
Gómez, Beatriz L.
Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
description "We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy. Copyright © 2014, American Society for Microbiology. All Rights Reserved."
format Artículo (Article)
author Caceres, Diego H.
Scheel, Christina M.
Tobón, Ángela M.
Cleveland, Angela Ahlquist
Restrepo, Ángela
Brandt, Mary E.
Chiller, Tom
Gómez, Beatriz L.
author_facet Caceres, Diego H.
Scheel, Christina M.
Tobón, Ángela M.
Cleveland, Angela Ahlquist
Restrepo, Ángela
Brandt, Mary E.
Chiller, Tom
Gómez, Beatriz L.
author_sort Caceres, Diego H.
title Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
title_short Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
title_full Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
title_fullStr Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
title_full_unstemmed Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy
title_sort validation of an enzyme-linked immunosorbent assay that detects histoplasma capsulatum antigenuria in colombian patients with aids for diagnosis and follow-up during therapy
publishDate 2014
url https://repository.urosario.edu.co/handle/10336/23675
https://doi.org/10.1128/CVI.00101-14
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