HIV Controllers Exhibit Effective CD8 + T Cell Recognition of HIV-1-Infected Non-activated CD4 + T Cells

"Even with sustained antiretroviral therapy, resting CD4 + T cells remain a persistent reservoir of HIV infection, representing a critical barrier to curing HIV. Here, we demonstrate that CD8 + T cells recognize infected, non-activated CD4 + T cells in the absence of de novo protein production,...

Descripción completa

Detalles Bibliográficos
Autores Principales: Monel, Blandine, McKeon, Annmarie, Lamothe-Molina, Pedro, Jani, Priya, Boucau, Julie, Pacheco, Yovana, Jones, R. Brad, Le Gall, Sylvie, Walker, Bruce D.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Elsevier B.V. 2019
Materias:
HIV
HLA
Acceso en línea:https://repository.urosario.edu.co/handle/10336/23642
https://doi.org/10.1016/j.celrep.2019.03.016