Critical role of HLA-DR?* binding peptides' peripheral flanking residues in fully-protective malaria vaccine development

"A vaccine candidate component must fit perfectly into the antigen presenting HLA-DR?* molecule's groove (or canonical nonapeptide) peptide binding region (PBR) during antigen presentation to the T-cell receptor (TCR), conforming a specific and stable macromolecular complex and induce an a...

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Detalles Bibliográficos
Autores Principales: Reyes C., Rojas-Luna R., Aza-Conde J., Tabares L., Patarroyo M.A., Patarroyo M.E.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Elsevier B.V. 2017
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/23517
https://doi.org/10.1016/j.bbrc.2017.05.123