Gauche+ side-chain orientation as a key factor in the search for an immunogenic peptide mixture leading to a complete fully protective vaccine

"Topological and stereo-electron characteristics are essential in major histocompability class II-peptide-T-cell receptor (MHC-p-TCR) complex formation for inducing an appropriate immune response. Modified high activity binding peptides (mHABPs) were synthesised for complete full protection ant...

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Detalles Bibliográficos
Autores Principales: "Bermúdez, Adriana, Calderon, Dayana, Moreno-Vranich, Armando, Almonacid, Hannia, Patarroyo, Manuel A., Poloche, Andrés, Patarroyo, Manuel E."
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Elsevier BV 2014
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/23461
https://doi.org/10.1016/j.vaccine.2014.02.003