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Characterization and antigenicity of the promising vaccine candidate Plasmodium vivax 34 kDa rhoptry antigen (Pv34)

This study describes the identification of the Plasmodium vivax rhoptry antigen Pv34 whose sequence was obtained based on homology comparison with the Plasmodium falciparum Pf34. The pv34 gene product was characterized by molecular biology and immunological techniques. Additionally, association of P...

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Detalles Bibliográficos
Autores Principales: Mongui, Alvaro, Angel, Diana I., Gallego, Gina, Reyes, Claudia, Martinez, Paola, Guhl, Felipe, Patarroyo, Manuel A.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2009
Materias:
Chloroquine
Gamma interferon
Interleukin 10
Interleukin 2
Interleukin 4
Interleukin 5
Malaria vaccine
Primaquine
Recombinant plasmodium vivax 34 antigen
Recombinant protein
Tumor necrosis factor alpha
Unclassified drug
Animal experiment
Article
Blood sampling
Cytokine release
Drug antigenicity
Human
Humoral immunity
Immunogenicity
Lymphocyte proliferation
Molecular biology
Monkey
Nonhuman
Nucleotide sequence
Peripheral blood mononuclear cell
Plasmodium vivax
Plasmodium vivax malaria
Priority journal
Protein blood level
Rabbit
Adult
Aged
Animals
Cytokines
Haplorhini
Humans
Malaria vaccines
Middle aged
Protozoan proteins
Rabbits
Pf34 homologue
Vaccine candidate
indirect
polyacrylamide gel
western
Blotting
Electrophoresis
Fluorescent antibody technique
Acceso en línea:https://repository.urosario.edu.co/handle/10336/23457
https://doi.org/10.1016/j.vaccine.2009.10.034

Internet

https://repository.urosario.edu.co/handle/10336/23457
https://doi.org/10.1016/j.vaccine.2009.10.034

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