Mass and secondary structure propensity of amino acids explain their mutability and evolutionary replacements

Why is an amino acid replacement in a protein accepted during evolution? The answer given by bioinformatics relies on the frequency of change of each amino acid by another one and the propensity of each to remain unchanged. We propose that these replacement rules are recoverable from the secondary s...

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Detalles Bibliográficos
Autores Principales: Bohórquez, Hugo J., Suárez, Carlos F., Patarroyo, Manuel E.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/23284
https://doi.org/10.1038/s41598-017-08041-7