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Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus

Objective Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production and altered type I interferon expression. Genetic surveys and genome-wide association studies have identified >30 SLE susceptibility genes. One of these genes, TNIP1, encodes the ABIN1 p...

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Detalles Bibliográficos
Autores Principales: Adrianto, Indra, Wang, Shaofeng, Wiley, Graham B., Lessard, Christopher J., Kelly, Jennifer A., Adler, Adam J., Glenn, Stuart B., Williams, Adrienne H., Ziegler, Julie T., Comeau, Mary E., Marion, Miranda C., Wakeland, Benjamin E., Liang, Chaoying, Kaufman, Kenneth M., Guthridge, Joel M., Alarcón?Riquelme, Marta E., Alarcón, Graciela S., Bae, Sang?Cheol, Kim, Jae?Hoon, Bin Joo, Young, Boackle, Susan A., Brown, Elizabeth E., Petri, Michelle, Ramsey?Goldman, Rosalind, Reveille, John D., Vilá, Luis M., Criswell, Lindsey A., Edberg, Jeffrey C., Freedman, Barry I., Gilkeson, Gary S., Jacob, Chaim O., James, Judith A., Kamen, Diane L., Kimberly, Robert P., Martín, Javier, Merrill, Joan T., Niewold, Timothy B., Pons?Estel, Bernardo A., Scofield, R. Hal, Stevens, Anne M., Tsao, Betty P., Vyse, Timothy J., Langefeld, Carl D., Harley, John B., Wakeland, Edward K., Moser, Kathy L., Montgomery, Courtney G., Gaffney, Patrick M., Anaya, Juan-Manuel
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2012
Materias:
Messenger RNA
Protein derivative
TNIP1 protein
Unclassified drug
Adult
African American
Article
Asian
B lymphocyte
Case control study
Controlled study
European American
Female
Gene expression
Gene mapping
Gene sequence
Genetic association
Genetic susceptibility
Genetic variability
Genome analysis
Haplotype
Hispanic
Human
Human cell
Major clinical study
Male
Nonhuman
Priority journal
Race difference
Reverse transcription polymerase chain reaction
Systemic lupus erythematosus
Western blotting
African Americans
Asian Americans
B-Lymphocytes
DNA-Binding Proteins
European Continental Ancestry Group
Genetic Markers
Genetic Predisposition to Disease
Haplotypes
Hispanic Americans
Humans
Intracellular Signaling Peptides and Proteins
Neoplasm Proteins
Risk Factors
United States
Signal Transducing
Single Nucleotide
Systemic
Transformed
Adaptor Proteins
Cell Line
Lupus Erythematosus
Polymorphism
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22988
https://doi.org/10.1002/art.34642

Internet

https://repository.urosario.edu.co/handle/10336/22988
https://doi.org/10.1002/art.34642

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