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Confirmation of an association between rs6822844 at the IL2-IL21 region and multiple autoimmune diseases: Evidence of a general susceptibility locus

Objective. Autoimmune diseases often have susceptibility genes in common, indicating similar molecular mechanisms. Increasing evidence suggests that rs6822844 at the IL2-IL21 region is strongly associated with multiple autoimmune diseases in individuals of European descent. This study was undertaken...

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Detalles Bibliográficos
Autores Principales: Maiti, Amit K., Kim?Howard, Xana, Viswanathan, Parvathi, Guillén, Laura, Deshmukh, Harshal, Direskeneli, Haner, Saruhan?Direskeneli, Güher, Cañas, Carlos, Tobön, Gabriel J., Sawalha, Amr H., Cherñavsky, Alejandra C., Nath, Swapan K., Rojas-Villarraga, Adriana, Anaya, Juan-Manuel
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2010
Materias:
Interleukin 2
Interleukin 21
Allele
Argentina
Article
Autoimmune disease
Behcet disease
Case control study
Celiac disease
Colombia
Controlled study
Data analysis
Enteritis
Europe
Evaluation
Evidence based medicine
Genetic association
Genetic susceptibility
Human
Insulin dependent diabetes mellitus
Major clinical study
Priority journal
Rheumatoid arthritis
Single nucleotide polymorphism
Sjoegren syndrome
Statistical significance
Systemic lupus erythematosus
Turkey (bird)
Ulcerative colitis
Autoimmune diseases
Case-control studies
Genetic predisposition to disease
Genotype
Humans
Interleukin-2
Interleukins
Phenotype
Sjogren's syndrome
Turkey
type 1
rheumatoid
single nucleotide
systemic
Arthritis
Diabetes mellitus
Lupus erythematosus
Polymorphism
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22955
https://doi.org/10.1002/art.27222

Internet

https://repository.urosario.edu.co/handle/10336/22955
https://doi.org/10.1002/art.27222

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