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Type I ROP16 regulates retinal inflammatory responses during ocular toxoplasmosis

Ocular toxoplasmosis (OT), mostly retinochorioditis, is a major feature of infection with the protozoan parasite Toxoplasma gondii. The pathophysiology of this infection is still largely elusive; especially mouse models are not yet well developed. In contrast, numerous in vitro studies showed the hi...

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Detalles Bibliográficos
Autores Principales: Rochet, Elise, Argy, Nicolas, Greigert, Valentin, Brunet, Julie, Sabou, Marcela, Marcellin, Luc, de-la-Torre, Alejandra, Sauer, Arnaud, Candolfi, Ermanno, Pfaff, Alexander W.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Public Library of Science 2019
Materias:
Cytokine
Protein rop16
Unclassified drug
Virulence factor
Protein tyrosine kinase
Protozoal protein
Allele
Animal cell
Animal experiment
Animal model
Aqueous humor
Cell proliferation
Chorioretinitis
Controlled study
Cytokine production
Female
Histopathology
Immunofluorescence
Mouse
Nonhuman
Ocular toxoplasmosis
Parasite virulence
Protein expression
Retina cell
Sequence homology
Th1 cell
Transgenic organism
Wild type
Classification
Disease model
Genetic engineering
Genetics
Immunology
Metabolism
Parasitology
Pathogenicity
Retina
Toxoplasma
Virulence
Animals
Cytokines
Mice
Protein-tyrosine kinases
Protozoan proteins
Toxoplasma gondii
Ocular
Rop16 protein
Disease models
Toxoplasmosis
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22832
https://doi.org/10.1371/journal.pone.0214310

Internet

https://repository.urosario.edu.co/handle/10336/22832
https://doi.org/10.1371/journal.pone.0214310

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