Ideal cardiovascular health predicts lower risk of abnormal liver enzymes levels in the Chilean National Health Survey (2009–2010)

High levels of gamma glutamyltransferase (gamma-GT) and alanine aminotransferase (ALT), as well as fatty liver index (FLI) has been associated with higher cardiovascular disease risk factors in adults. The aim of this study was to examine the relationship between gamma-GT, ALT, and fatty liver index...

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Autores Principales: García-Hermoso, Antonio, Hackney, Anthony C., Ramírez-Vélez, Robinson
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22826
https://doi.org/10.1371/journal.pone.0185908
id ir-10336-22826
recordtype dspace
spelling ir-10336-228262022-08-29T15:22:18Z Ideal cardiovascular health predicts lower risk of abnormal liver enzymes levels in the Chilean National Health Survey (2009–2010) García-Hermoso, Antonio Hackney, Anthony C. Ramírez-Vélez, Robinson Alanine aminotransferase Gamma glutamyltransferase Glucose Alanine aminotransferase Gamma glutamyltransferase Alanine aminotransferase blood level Blood pressure Body mass Cardiovascular risk Controlled study Digestive system disease assessment Enzyme liver level Fatty liver index Gamma glutamyl transferase blood level Health behavior Health survey Liver level Medication compliance Physical activity Prevalence Smoking Aged Blood Cardiovascular system Enzymology Liver Middle aged Risk factor Alanine transaminase Cardiovascular system Gamma-glutamyltransferase Humans Middle aged Risk factors High levels of gamma glutamyltransferase (gamma-GT) and alanine aminotransferase (ALT), as well as fatty liver index (FLI) has been associated with higher cardiovascular disease risk factors in adults. The aim of this study was to examine the relationship between gamma-GT, ALT, and fatty liver index FLI levels across a gradient number of ideal cardiovascular health metrics in a representative sample of adults from the Chilean National Health Survey 2009–2010. Data from 1,023 men and 1,449 women (? 15 years) from the Chilean Health Survey 2009–2010 were analyzed. Ideal cardiovascular health was defined as meeting ideal levels of the following components: four behaviours (smoking, body mass index, physical activity and diet adherence) and three factors (total cholesterol, blood pressure and fasting glucose). Adults were grouped into three categories according to their number of ideal cardiovascular health metrics: ideal (5–7 metrics), intermediate (3–4 metrics), and poor (0–2 metrics). Blood levels of gamma-GT and ALT were measured and the FLI was calculated. A higher number of ideal cardiovascular health index metric was associated with lower gamma-GT, ALT and FLI (p from trend analysis less than 0.001). Also, adults meeting at least 3–4 metrics were predicted less likely to have prevalence of abnormal levels of gamma-GT and FLI (p less than 0.001) compared to adults who met only 0–2 metrics. These findings reinforce the usefulness of the ideal cardiovascular health metrics proposed by the American Heart Association as a tool to identify target subjects and promote cardiovascular health in South-American adults. © 2017 García-Hermoso et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 2017 2020-05-25T23:58:14Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 19326203 https://repository.urosario.edu.co/handle/10336/22826 https://doi.org/10.1371/journal.pone.0185908 eng info:eu-repo/semantics/openAccess application/pdf Public Library of Science instname:Universidad del Rosario
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic Alanine aminotransferase
Gamma glutamyltransferase
Glucose
Alanine aminotransferase
Gamma glutamyltransferase
Alanine aminotransferase blood level
Blood pressure
Body mass
Cardiovascular risk
Controlled study
Digestive system disease assessment
Enzyme liver level
Fatty liver index
Gamma glutamyl transferase blood level
Health behavior
Health survey
Liver level
Medication compliance
Physical activity
Prevalence
Smoking
Aged
Blood
Cardiovascular system
Enzymology
Liver
Middle aged
Risk factor
Alanine transaminase
Cardiovascular system
Gamma-glutamyltransferase
Humans
Middle aged
Risk factors
spellingShingle Alanine aminotransferase
Gamma glutamyltransferase
Glucose
Alanine aminotransferase
Gamma glutamyltransferase
Alanine aminotransferase blood level
Blood pressure
Body mass
Cardiovascular risk
Controlled study
Digestive system disease assessment
Enzyme liver level
Fatty liver index
Gamma glutamyl transferase blood level
Health behavior
Health survey
Liver level
Medication compliance
Physical activity
Prevalence
Smoking
Aged
Blood
Cardiovascular system
Enzymology
Liver
Middle aged
Risk factor
Alanine transaminase
Cardiovascular system
Gamma-glutamyltransferase
Humans
Middle aged
Risk factors
García-Hermoso, Antonio
Hackney, Anthony C.
Ramírez-Vélez, Robinson
Ideal cardiovascular health predicts lower risk of abnormal liver enzymes levels in the Chilean National Health Survey (2009–2010)
description High levels of gamma glutamyltransferase (gamma-GT) and alanine aminotransferase (ALT), as well as fatty liver index (FLI) has been associated with higher cardiovascular disease risk factors in adults. The aim of this study was to examine the relationship between gamma-GT, ALT, and fatty liver index FLI levels across a gradient number of ideal cardiovascular health metrics in a representative sample of adults from the Chilean National Health Survey 2009–2010. Data from 1,023 men and 1,449 women (? 15 years) from the Chilean Health Survey 2009–2010 were analyzed. Ideal cardiovascular health was defined as meeting ideal levels of the following components: four behaviours (smoking, body mass index, physical activity and diet adherence) and three factors (total cholesterol, blood pressure and fasting glucose). Adults were grouped into three categories according to their number of ideal cardiovascular health metrics: ideal (5–7 metrics), intermediate (3–4 metrics), and poor (0–2 metrics). Blood levels of gamma-GT and ALT were measured and the FLI was calculated. A higher number of ideal cardiovascular health index metric was associated with lower gamma-GT, ALT and FLI (p from trend analysis less than 0.001). Also, adults meeting at least 3–4 metrics were predicted less likely to have prevalence of abnormal levels of gamma-GT and FLI (p less than 0.001) compared to adults who met only 0–2 metrics. These findings reinforce the usefulness of the ideal cardiovascular health metrics proposed by the American Heart Association as a tool to identify target subjects and promote cardiovascular health in South-American adults. © 2017 García-Hermoso et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
format Artículo (Article)
author García-Hermoso, Antonio
Hackney, Anthony C.
Ramírez-Vélez, Robinson
author_facet García-Hermoso, Antonio
Hackney, Anthony C.
Ramírez-Vélez, Robinson
author_sort García-Hermoso, Antonio
title Ideal cardiovascular health predicts lower risk of abnormal liver enzymes levels in the Chilean National Health Survey (2009–2010)
title_short Ideal cardiovascular health predicts lower risk of abnormal liver enzymes levels in the Chilean National Health Survey (2009–2010)
title_full Ideal cardiovascular health predicts lower risk of abnormal liver enzymes levels in the Chilean National Health Survey (2009–2010)
title_fullStr Ideal cardiovascular health predicts lower risk of abnormal liver enzymes levels in the Chilean National Health Survey (2009–2010)
title_full_unstemmed Ideal cardiovascular health predicts lower risk of abnormal liver enzymes levels in the Chilean National Health Survey (2009–2010)
title_sort ideal cardiovascular health predicts lower risk of abnormal liver enzymes levels in the chilean national health survey (2009–2010)
publisher Public Library of Science
publishDate 2017
url https://repository.urosario.edu.co/handle/10336/22826
https://doi.org/10.1371/journal.pone.0185908
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score 12,131701