A pharmacogenomic dissection of a Rosuvastatin-induced rhabdomyolysis case evokes the polygenic nature of adverse drug reactions

"Rosuvastatin, is a widely-used statin for the treatment of hypercholesterolemia and the prevention of cardiovascular diseases. Although rosuvastatin is well tolerated, about 3/10.000 patients can suffer severe myopathy. Rhabdomyolysis is a severe medical condition that causes injury to the ske...

Descripción completa

Detalles Bibliográficos
Autores Principales: "Calderon-Ospina, Carlos Alberto, Hernández-Sómerson, Mario, García, Ana María, Mejia, Adriana, Tamayo-Agudelo, Caroll, Laissue, Paul, Fonseca Mendoza, Dora Janeth"
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Dove Medical Press Ltd 2020
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22797
https://doi.org/10.2147/PGPM.S228709