Creating and validating a warfarin pharmacogenetic dosing algorithm for colombian patients

"Purpose: Warfarin is an oral anticoagulant associated with adverse reaction to drugs due to wide inter-and intra-individual dosage variability. Warfarin dosage has been related to non-genetic and genetic factors. CYP2C9 and VKORC1 gene polymorphisms affect warfarin metabolism and dosage. Due t...

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Detalles Bibliográficos
Autores Principales: Galvez, Jubby Marcela, Restrepo, Carlos Martin, Contreras, Nora Constanza, Alvarado, Clara, Calderón-Ospina, Carlos-Alberto, Peña, Nidia, Cifuentes, Ricardo A, Duarte, Daniela, Laissue, Paul, Fonseca, Dora Janeth
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Dove Medical Press Ltd 2018
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22796
https://doi.org/10.2147/PGPM.S170515