Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women

Objectives: The aims of the present systematic review and meta-analysis were to determine the relationship between muscular strength and all-cause mortality risk and to examine the sex-specific impact of muscular strength on all-cause mortality in an apparently healthy population. Data Sources: Two...

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Autores Principales: García-Hermoso A., Cavero-Redondo I., Ramírez-Vélez R., Ruiz J.R., Ortega F.B., Lee D.-C., Martínez-Vizcaíno V.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: W.B. Saunders 2018
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22789
https://doi.org/10.1016/j.apmr.2018.01.008
id ir-10336-22789
recordtype dspace
spelling ir-10336-227892022-05-02T12:37:14Z Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women García-Hermoso A. Cavero-Redondo I. Ramírez-Vélez R. Ruiz J.R. Ortega F.B. Lee D.-C. Martínez-Vizcaíno V. Adult All cause mortality Article Cohort analysis Controlled study Data extraction Data synthesis Death Embase Female Follow up Grip strength Hazard ratio Human Knee Male Medline Meta analysis Mortality risk Muscle strength Risk assessment Systematic review Aged Cause of death Health survey Middle aged Mortality Muscle disease Muscle strength Pathophysiology Physiology Proportional hazards model Sex ratio Adult Aged Cause of death Cohort studies Female Humans Male Middle aged Muscle strength Muscular diseases Population surveillance Proportional hazards models Sex distribution Death Hand strength Leg strength Muscles Objectives: The aims of the present systematic review and meta-analysis were to determine the relationship between muscular strength and all-cause mortality risk and to examine the sex-specific impact of muscular strength on all-cause mortality in an apparently healthy population. Data Sources: Two authors systematically searched MEDLINE, EMBASE and SPORTDiscus databases and conducted manual searching of reference lists of selected articles. Study Selection: Eligible cohort studies were those that examined the association of muscular strength with all-cause mortality in an apparently healthy population. The hazard ratio (HR) estimates with 95% confidence interval (CI) were pooled by using random effects meta-analysis models after assessing heterogeneity across studies. Data Extraction: Two authors independently extracted data. Data Synthesis: Thirty-eight studies with 1,907,580 participants were included in the meta-analysis. The included studies had a total of 63,087 deaths. Higher levels of handgrip strength were associated with a reduced risk of all-cause mortality (HR=0.69; 95% CI, 0.64-0.74) compared with lower muscular strength, with a slightly stronger association in women (HR=0.60; 95% CI, 0.51-0.69) than men (HR=0.69; 95% CI, 0.62-0.77) (all P less than .001). Also, adults with higher levels of muscular strength, as assessed by knee extension strength test, had a 14% lower risk of death (HR=0.86: 95% CI, 0.80-0.93; P less than .001) compared with adults with lower muscular strength. Conclusions: Higher levels of upper- and lower-body muscular strength are associated with a lower risk of mortality in adult population, regardless of age and follow-up period. Muscular strength tests can be easily performed to identify people with lower muscular strength and, consequently, with an increased risk of mortality. © 2018 American Congress of Rehabilitation Medicine 2018 2020-05-25T23:58:02Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 1532821X 00039993 https://repository.urosario.edu.co/handle/10336/22789 https://doi.org/10.1016/j.apmr.2018.01.008 eng info:eu-repo/semantics/openAccess application/pdf W.B. Saunders instname:Universidad del Rosario
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic Adult
All cause mortality
Article
Cohort analysis
Controlled study
Data extraction
Data synthesis
Death
Embase
Female
Follow up
Grip strength
Hazard ratio
Human
Knee
Male
Medline
Meta analysis
Mortality risk
Muscle strength
Risk assessment
Systematic review
Aged
Cause of death
Health survey
Middle aged
Mortality
Muscle disease
Muscle strength
Pathophysiology
Physiology
Proportional hazards model
Sex ratio
Adult
Aged
Cause of death
Cohort studies
Female
Humans
Male
Middle aged
Muscle strength
Muscular diseases
Population surveillance
Proportional hazards models
Sex distribution
Death
Hand strength
Leg strength
Muscles
spellingShingle Adult
All cause mortality
Article
Cohort analysis
Controlled study
Data extraction
Data synthesis
Death
Embase
Female
Follow up
Grip strength
Hazard ratio
Human
Knee
Male
Medline
Meta analysis
Mortality risk
Muscle strength
Risk assessment
Systematic review
Aged
Cause of death
Health survey
Middle aged
Mortality
Muscle disease
Muscle strength
Pathophysiology
Physiology
Proportional hazards model
Sex ratio
Adult
Aged
Cause of death
Cohort studies
Female
Humans
Male
Middle aged
Muscle strength
Muscular diseases
Population surveillance
Proportional hazards models
Sex distribution
Death
Hand strength
Leg strength
Muscles
García-Hermoso A.
Cavero-Redondo I.
Ramírez-Vélez R.
Ruiz J.R.
Ortega F.B.
Lee D.-C.
Martínez-Vizcaíno V.
Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women
description Objectives: The aims of the present systematic review and meta-analysis were to determine the relationship between muscular strength and all-cause mortality risk and to examine the sex-specific impact of muscular strength on all-cause mortality in an apparently healthy population. Data Sources: Two authors systematically searched MEDLINE, EMBASE and SPORTDiscus databases and conducted manual searching of reference lists of selected articles. Study Selection: Eligible cohort studies were those that examined the association of muscular strength with all-cause mortality in an apparently healthy population. The hazard ratio (HR) estimates with 95% confidence interval (CI) were pooled by using random effects meta-analysis models after assessing heterogeneity across studies. Data Extraction: Two authors independently extracted data. Data Synthesis: Thirty-eight studies with 1,907,580 participants were included in the meta-analysis. The included studies had a total of 63,087 deaths. Higher levels of handgrip strength were associated with a reduced risk of all-cause mortality (HR=0.69; 95% CI, 0.64-0.74) compared with lower muscular strength, with a slightly stronger association in women (HR=0.60; 95% CI, 0.51-0.69) than men (HR=0.69; 95% CI, 0.62-0.77) (all P less than .001). Also, adults with higher levels of muscular strength, as assessed by knee extension strength test, had a 14% lower risk of death (HR=0.86: 95% CI, 0.80-0.93; P less than .001) compared with adults with lower muscular strength. Conclusions: Higher levels of upper- and lower-body muscular strength are associated with a lower risk of mortality in adult population, regardless of age and follow-up period. Muscular strength tests can be easily performed to identify people with lower muscular strength and, consequently, with an increased risk of mortality. © 2018 American Congress of Rehabilitation Medicine
format Artículo (Article)
author García-Hermoso A.
Cavero-Redondo I.
Ramírez-Vélez R.
Ruiz J.R.
Ortega F.B.
Lee D.-C.
Martínez-Vizcaíno V.
author_facet García-Hermoso A.
Cavero-Redondo I.
Ramírez-Vélez R.
Ruiz J.R.
Ortega F.B.
Lee D.-C.
Martínez-Vizcaíno V.
author_sort García-Hermoso A.
title Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women
title_short Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women
title_full Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women
title_fullStr Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women
title_full_unstemmed Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women
title_sort muscular strength as a predictor of all-cause mortality in an apparently healthy population: a systematic review and meta-analysis of data from approximately 2 million men and women
publisher W.B. Saunders
publishDate 2018
url https://repository.urosario.edu.co/handle/10336/22789
https://doi.org/10.1016/j.apmr.2018.01.008
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score 12,131701