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Passive transfer of Plasmodium falciparum MSP-2 pseudopeptide-induced antibodies efficiently controlled parasitemia in Plasmodium berghei-infected mice

We have developed monoclonal antibodies directed against the pseudopeptide ?-130, derived from the highly conserved malarial antigen Plasmodium falciparum merozoite surface protein 2 (MSP-2), for obtaining novel molecular tools with potential applications in the control of malaria. Following isotype...

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Detalles Bibliográficos
Autores Principales: Martínez, Paola A., Yandar, Nubia, Lesmes, Liliana P., Forero, Martha, Pérez-Leal, Oscar, Patarroyo, Manuel Elkin, Lozano, José Manuel
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2009
Materias:
Immunoglobulin
Immunoglobulin class
Malaria vaccine
Merozoite surface protein 2
Monoclonal antibody
Monoclonal antibody anti pseudopeptide psi 130
Pseudopeptide
Unclassified drug
Animal cell
Animal experiment
Animal model
Animal tissue
Article
Controlled study
Drug design
Drug mechanism
Drug synthesis
Female
Mouse
Nonhuman
Parasitemia
Passive immunization
Plasmodium berghei infection
Plasmodium falciparum
Priority journal
Animals
Antibodies, protozoan
Antigens, protozoan
Disease models, animal
Immunization, passive
Malaria
Mice
Mice, inbred balb c
Plasmodium berghei
Protozoan proteins
Recombinant proteins
Murinae
Mus
Anti-malarial vaccine
Ig isotype
In vivo neutralizing activity
Murine malarial infection
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22784
https://doi.org/10.1016/j.peptides.2008.10.022

Internet

https://repository.urosario.edu.co/handle/10336/22784
https://doi.org/10.1016/j.peptides.2008.10.022

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