Imagen de Portada

Transcriptional responses of Leishmania (Leishmania) amazonensis in the presence of trivalent sodium stibogluconate

Background: In the last decade, resistance to antimonials has become a serious problem due to the emergence of drug-resistant strains. Therefore, understanding the mechanisms used by Leishmania parasites to survive under drug pressure is essential, particularly for species of medical-veterinary impo...

Descripción completa

Detalles Bibliográficos
Autores Principales: Patino, Luz H., Muskus, Carlos, Ramírez, Juan David
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: BioMed Central Ltd. 2019
Materias:
Antimony
Autophagy related protein
Stibogluconate sodium
Transcriptome
Antimony gluconate
Antiprotozoal agent
Protozoal dna
Antiparasitic activity
Article
Autophagy
Cell cycle
Cell death
Controlled study
Cytoskeleton
Drug response
Fatty acid metabolism
Gene expression
Genetic code
Genetic identification
Leishmania
Leishmania amazonensis
Nonhuman
Parasite survival
Promastigote
Rna sequence
Stress
Transcriptomics
Upregulation
Drug effect
Drug resistance
Gene expression profiling
Gene ontology
Genetics
Phenotype
Sequence analysis
Antimony sodium gluconate
Antiprotozoal agents
Up-regulation
Deg
Diffuse leishmaniasis
Hierarchical cluster analysis (hca)
Principal components analysis (pca)
Resistance
Transcript
protozoan
rna
Dna
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22752
https://doi.org/10.1186/s13071-019-3603-8

Internet

https://repository.urosario.edu.co/handle/10336/22752
https://doi.org/10.1186/s13071-019-3603-8

Ejemplares similares