DNA demethylation agent 5azadC downregulates HPV16 E6 expression in cervical cancer cell lines independently of TBX2 expression
HPV16 is the most carcinogenic human papillomavirus and causes >50% of cervical cancers, the majority of anal cancers and 30% of oropharyngeal squamous cell carcinomas. HPV carcinogenesis relies on the continuous expression of the two main viral oncoproteins E6 and E7 that target >150 cellular...
Autores Principales: | , , , , , , , , , , , |
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Formato: | Artículo (Article) |
Lenguaje: | Inglés (English) |
Publicado: |
Spandidos Publications
2020
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Materias: | |
Acceso en línea: | https://repository.urosario.edu.co/handle/10336/22720 https://doi.org/10.3892/ol.2019.11158 |