Differential regulation of AKT, MAPK and GSK3? during C2-ceramide-induced neuronal death

Evidence has implicated apoptosis as a mechanism underlying cell demise in diverse neurodegenerative diseases including Parkinson's disease (PD). Endogenous toxins and other stress signals activate the sphingomyelin pathway increasing the levels of ceramide, an important regulator of cell death...

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Detalles Bibliográficos
Autores Principales: Arboleda, Gonzalo, Cárdenas, Yolanda, Rodríguez, Yeldy, Morales, Luis Carlos, Matheus, Luisa, Arboleda, Humberto
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2010
Materias:
Akt
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22659
https://doi.org/10.1016/j.neuro.2010.08.001

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