Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor

"Pregnancy-associated malaria commonly involves the binding of Plasmodium falciparum-infected erythrocytes to placental chondroitin sulfate A (CSA) through the PfEMP1-VAR2CSA protein. VAR2CSA is translationally repressed by an upstream open reading frame. In this study, we report that the P. fa...

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Detalles Bibliográficos
Autores Principales: Chan S., Frasch A., Mandava C.S., Ch'Ng J.-H., Quintana M.D.P., Vesterlund M., Ghorbal M., Joannin N., Franzén O., Lopez-Rubio J.-J., Barbieri S., Lanzavecchia A., Sanyal S., Wahlgren M.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22642
https://doi.org/10.1038/nmicrobiol.2017.68