Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

Sjögren's syndrome is a common autoimmune disease (affecting ?0.7% of European Americans) that typically presents as keratoconjunctivitis sicca and xerostomia. Here we report results of a large-scale association study of Sjögren's syndrome. In addition to strong association within the huma...

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Autores Principales: Lessard, Christopher J, Li, He, Adrianto, Indra, Ice, John A, Rasmussen, Astrid, Grundahl, Kiely M, Kelly, Jennifer A, Dozmorov, Mikhail G, Miceli-Richard, Corinne, Bowman, Simon, Lester, Sue, Eriksson, Per, Eloranta, Maija-Leena, Brun, Johan G, Gøransson, Lasse G, Harboe, Erna, Guthridge, Joel M, Kaufman, Kenneth M, Kvarnström, Marika, Jazebi, Helmi, Graham, Deborah S Cunninghame, Grandits, Martha E, Nazmul-Hossain, Abu N M, Patel, Ketan, Adler, Adam J, Maier-Moore, Jacen S, Farris, A Darise, Brennan, Michael T, Lessard, James A, Chodosh, James, Gopalakrishnan, Rajaram, Hefner, Kimberly S, Houston, Glen D, Huang, Andrew J W, Hughes, Pamela J, Lewis, David M, Radfar, Lida, Rohrer, Michael D, Stone, Donald U, Wren, Jonathan D, Vyse, Timothy J, Gaffney, Patrick M, James, Judith A, Omdal, Roald, Wahren-Herlenius, Marie, Illei, Gabor G, Witte, Torsten, Jonsson, Roland, Rischmueller, Maureen, Rönnblom, Lars, Nordmark, Gunnel, Ng, Wan-Fai, Mariette, Xavier, Anaya, Juan-Manuel, Rhodus, Nelson L, Segal, Barbara M, Scofield, R Hal, Montgomery, Courtney G, Harley, John B, Sivils, Kathy L
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2013
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22639
https://doi.org/10.1038/ng.2792