Reproductive clonality in protozoan pathogens - Truth or artefact?
The debate around the frequency and importance of genetic exchange in parasitic protozoa is now several decades old. Recently, fresh assertions have been made that predominant clonal evolution explains the population structures of several key protozoan pathogens. Here, we present an alternative pers...
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2014
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Acceso en línea: | https://repository.urosario.edu.co/handle/10336/22613 https://doi.org/10.1111/mec.12872 |
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ir-10336-226132022-05-02T12:37:14Z Reproductive clonality in protozoan pathogens - Truth or artefact? Ramírez, Juan David Llewellyn, Martin S. Clonal evolution Clonal variation Evolution Gene exchange Genetic variability Genetics Giardia Physiology Protozoan pathogens Review Sexuality Toxoplasma Clonality Genetic exchange Protozoan pathogens Sexuality Biological evolution Clonal evolution Genetic variation Giardia Toxoplasma Clonality Genetic exchange Protozoan pathogens Sexuality The debate around the frequency and importance of genetic exchange in parasitic protozoa is now several decades old. Recently, fresh assertions have been made that predominant clonal evolution explains the population structures of several key protozoan pathogens. Here, we present an alternative perspective. On the assumption that much apparent clonality may be an artefact of inadequate sampling and study design, we review current research to define why sex might be so difficult to detect in protozoan parasite populations. In doing so, we contrast laboratory models of genetic exchange in parasitic protozoa with natural patterns of genetic diversity and consider the fitness advantage of sex at different evolutionary scales. We discuss approaches to improve the accuracy of efforts to characterize genetic exchange in the field. We also examine the implications of the first population genomic studies for the debate around sex and clonality in parasitic protozoa and discuss caveats for the future. © 2014 John Wiley and Sons Ltd. 2014 2020-05-25T23:57:08Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 1365294X 09621083 https://repository.urosario.edu.co/handle/10336/22613 https://doi.org/10.1111/mec.12872 eng info:eu-repo/semantics/openAccess application/pdf Blackwell Publishing Ltd instname:Universidad del Rosario |
institution |
EdocUR - Universidad del Rosario |
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DSpace |
language |
Inglés (English) |
topic |
Clonal evolution Clonal variation Evolution Gene exchange Genetic variability Genetics Giardia Physiology Protozoan pathogens Review Sexuality Toxoplasma Clonality Genetic exchange Protozoan pathogens Sexuality Biological evolution Clonal evolution Genetic variation Giardia Toxoplasma Clonality Genetic exchange Protozoan pathogens Sexuality |
spellingShingle |
Clonal evolution Clonal variation Evolution Gene exchange Genetic variability Genetics Giardia Physiology Protozoan pathogens Review Sexuality Toxoplasma Clonality Genetic exchange Protozoan pathogens Sexuality Biological evolution Clonal evolution Genetic variation Giardia Toxoplasma Clonality Genetic exchange Protozoan pathogens Sexuality Ramírez, Juan David Llewellyn, Martin S. Reproductive clonality in protozoan pathogens - Truth or artefact? |
description |
The debate around the frequency and importance of genetic exchange in parasitic protozoa is now several decades old. Recently, fresh assertions have been made that predominant clonal evolution explains the population structures of several key protozoan pathogens. Here, we present an alternative perspective. On the assumption that much apparent clonality may be an artefact of inadequate sampling and study design, we review current research to define why sex might be so difficult to detect in protozoan parasite populations. In doing so, we contrast laboratory models of genetic exchange in parasitic protozoa with natural patterns of genetic diversity and consider the fitness advantage of sex at different evolutionary scales. We discuss approaches to improve the accuracy of efforts to characterize genetic exchange in the field. We also examine the implications of the first population genomic studies for the debate around sex and clonality in parasitic protozoa and discuss caveats for the future. © 2014 John Wiley and Sons Ltd. |
format |
Artículo (Article) |
author |
Ramírez, Juan David Llewellyn, Martin S. |
author_facet |
Ramírez, Juan David Llewellyn, Martin S. |
author_sort |
Ramírez, Juan David |
title |
Reproductive clonality in protozoan pathogens - Truth or artefact? |
title_short |
Reproductive clonality in protozoan pathogens - Truth or artefact? |
title_full |
Reproductive clonality in protozoan pathogens - Truth or artefact? |
title_fullStr |
Reproductive clonality in protozoan pathogens - Truth or artefact? |
title_full_unstemmed |
Reproductive clonality in protozoan pathogens - Truth or artefact? |
title_sort |
reproductive clonality in protozoan pathogens - truth or artefact? |
publisher |
Blackwell Publishing Ltd |
publishDate |
2014 |
url |
https://repository.urosario.edu.co/handle/10336/22613 https://doi.org/10.1111/mec.12872 |
_version_ |
1740172949119303680 |
score |
12,131701 |