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Identifying and characterising PPE7 (Rv0354c) high activity binding peptides and their role in inhibiting cell invasion

This study was aimed at characterising the PPE7 protein from the PE/PPE protein family. The presence and transcription of the rv0354c gene in the Mycobacterium tuberculosis complex was determined and the subcellular localisation of the PPE7 protein on mycobacterial membrane was confirmed by immunoel...

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Detalles Bibliográficos
Autores Principales: Díaz D.P., Ocampo M., Varela Y., Curtidor H., Patarroyo M.A., Patarroyo M.E.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Springer New York LLC 2017
Materias:
Bacterial protein
Peptide
Ppe7 protein
Unclassified drug
Bcg vaccine
A-549 cell line
Amino acid sequence
Article
Bacterial gene
Binding affinity
Carboxy terminal sequence
Cell invasion
Cellular distribution
Controlled study
Host cell
Human
Human cell
Immunoelectron microscopy
In vitro study
Macrophage
Microscope
Mycobacterium tuberculosis
Mycobacterium tuberculosis complex
Nonhuman
Protein binding
U-937 cell line
Cell membrane
Genetics
Metabolism
Pathogenicity
Pathology
Ultrastructure
A549 cells
Bacterial proteins
Humans
Tuberculosis vaccines
U937 cells
High activity binding peptide
Mycobacterium tuberculosis h37rv
Synthetic peptide
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22603
https://doi.org/10.1007/s11010-017-2962-8

Internet

https://repository.urosario.edu.co/handle/10336/22603
https://doi.org/10.1007/s11010-017-2962-8

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