Size polymorphism and low sequence diversity in the locus encoding the Plasmodium vivax rhoptry neck protein 4 (PvRON4) in Colombian isolates

"Background: Designing a vaccine against Plasmodium vivax has focused on selecting antigens involved in invasion mechanisms that must have domains with low polymorphism for avoiding allele-specific immune responses. The rhoptry neck protein 4 (RON4) forms part of the tight junction, which is es...

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Detalles Bibliográficos
Autores Principales: Buitrago, Sindy P., Garzón-Ospina, Diego, Patarroyo, Manuel A.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: BioMed Central Ltd. 2016
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22548
https://doi.org/10.1186/s12936-016-1563-4