Existencias: Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA

Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA

Objectives Systemic lupus erythematosus (SLE; OMIM 152700) is characterised by the production of antibodies to nuclear antigens. We previously identified variants in complement receptor 2 (CR2/CD21) that were associated with decreased risk of SLE. This study aimed to identify the causal variant for...

Descripción completa

Detalles Bibliográficos
Autores Principales:	Zhao, Jian, Giles, Brendan M, Taylor, Rhonda L, Yette, Gabriel A, Lough, Kara M, Ng, Han Leng, Abraham, Lawrence J, Wu, Hui, Kelly, Jennifer A, Glenn, Stuart B, Adler, Adam J, Williams, Adrienne H, Comeau, Mary E, Ziegler, Julie T, Marion, Miranda, Alarcón-Riquelme, Marta E, Alarcón, Graciela S, Anaya, Juan-Manuel, Bae, Sang-Cheol, Kim, Dam, Lee, Hye-Soon, Criswell, Lindsey A, Freedman, Barry I, Gilkeson, Gary S, Guthridge, Joel M, Jacob, Chaim O, James, Judith A, Kamen, Diane L, Merrill, Joan T, Sivils, Kathy Moser, Niewold, Timothy B, Petri, Michelle A, Ramsey-Goldman, Rosalind, Reveille, John D, Scofield, R Hal, Stevens, Anne M, Vilá, Luis M, Vyse, Timothy J, Kaufman, Kenneth M, Harley, John B, Langefeld, Carl D, Gaffney, Patrick M, Brown, Elizabeth E, Edberg, Jeffrey C, Kimberly, Robert P, Ulgiati, Daniela, Tsao, Betty P, Boackle, Susan A
Formato:	Artículo (Article)
Lenguaje:	Inglés (English)
Publicado:	BMJ Publishing Group 2016
Materias:	Complement component C3b receptor Complement receptor Complement receptor 2 Double stranded DNA antibody Messenger RNA Transcription factor CTCF Unclassified drug Antinuclear antibody Complement component C3d receptor CR1 protein, human DNA Transcription factor Allele Article B lymphocyte Case control study Chromatin immunoprecipitation Controlled study DNA protein complex Flow cytometry Gel mobility shift assay Genetic association Genetic variability Genotype Human Intron Major clinical study Pathogenesis Priority journal Real time polymerase chain reaction Systemic lupus erythematosus Adolescent Adult Biosynthesis Blood Genetic predisposition Genetic variation Genetics Haplotype Immunology Metabolism Middle aged Phenotype Procedures Risk assessment Single nucleotide polymorphism Young adult B-Lymphocyte Subsets Case-Control Studies Genetic Predisposition to Disease Genetic Variation Haplotypes Humans Middle Aged Receptors, Complement 3d Risk Assessment Transcription Factors Young Adult Systemic Antinuclear Single Nucleotide Antibodies Lupus Erythematosus Polymorphism
Acceso en línea:	https://repository.urosario.edu.co/handle/10336/22444 https://doi.org/10.1136/annrheumdis-2014-205584

Internet

https://repository.urosario.edu.co/handle/10336/22444
https://doi.org/10.1136/annrheumdis-2014-205584

Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA

Internet

Ejemplares similares