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Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries

Objective: Systemic lupus erythematosus (SLE; OMIM 152700) is a chronic autoimmune disease for which the aetiology includes genetic and environmental factors. ITGAM, integrin ?M(complement component 3 receptor 3 subunit) encoding a ligand for intracellular adhesion molecule (ICAM) proteins, is an es...

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Detalles Bibliográficos
Autores Principales: Kim, Kwangwoo, Brown, Elizabeth E, Choi, Chan-Bum, Alarcón-Riquelme, Marta E, Kelly, Jennifer A, Glenn, Stuart B, Ojwang, Joshua O, Adler, Adam, Lee, Hye-Soon, Boackle, Susan A, Criswell, Lindsey A, Alarcón, Graciela S, Edberg, Jeffrey C, Stevens, Anne M, Jacob, Chaim O, Gilkeson, Gary S, Kamen, Diane L, Tsao, Betty P, Anaya, Juan-Manuel, Guthridge, Joel M, Nath, Swapan K, Richardson, Bruce, Sawalha, Amr H, Kang, Young Mo, Shim, Seung Cheol, Suh, Chang-Hee, Lee, Soo-Kon, Kim, Chang-sik, Merrill, Joan T, Petri, Michelle, Ramsey-Goldman, Rosalind, Vilá, Luis M, Niewold, Timothy B, Martin, Javier, Pons-Estel, Bernardo A, Vyse, Timothy J, Freedman, Barry I, Moser, Kathy L, Gaffney, Patrick M, Williams, Adrienne, Comeau, Mary, Reveille, John D, James, Judith A, Scofield, R Hal, Langefeld, Carl D, Kaufman, Kenneth M, Harley, John B, Kang, Changwon, Kimberly, Robert P, Bae, Sang-Cheol
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2012
Materias:
Alpha integrin
Integrin alpha m
Intercellular adhesion molecule 1
Unclassified drug
Article
Asian
Case control study
Caucasian
Chromosome 19p
Controlled study
Gene expression
Gene interaction
Gene locus
Genetic association
Genetic risk
Genetic susceptibility
Genetic variability
Hispanic
Human
Intercellular adhesion molecule 1 gene
Intercellular adhesion molecule 4 gene
Intercellular adhesion molecule 5 gene
Korean
Major clinical study
Negro
Priority journal
Quantitative trait locus
Single nucleotide polymorphism
Systemic lupus erythematosus
Cell adhesion molecules
Continental population groups
Genetic markers
Genetic predisposition to disease
Genome-wide association study
Humans
Intercellular adhesion molecule-1
Nerve tissue proteins
systemic
single nucleotide
population
Genetics
Lupus erythematosus
Polymorphism
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22411
https://doi.org/10.1136/annrheumdis-2011-201110

Internet

https://repository.urosario.edu.co/handle/10336/22411
https://doi.org/10.1136/annrheumdis-2011-201110

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