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"ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry"

"Purpose: It was hypothesised that the coding variant (R77H), rs1143679, within ITGAM could predict specific clinical manifestations associated with systemic lupus erythematosus (SLE). Method: To assess genetic association, 2366 patients with SLE and 2931 unaffected controls with European ances...

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Detalles Bibliográficos
Autores Principales: Kim-Howard, Xana, Maiti, Amit K, Anaya, Juan-Manuel, Bruner, Gail R, Brown, Elizabeth, Merrill, Joan T, Edberg, Jeffrey C, Petri, Michelle A, Reveille, John D, Ramsey-Goldman, Rosalind, Alarcon, Graciela S, Vyse, Timothy J, Gilkeson, Gary, Kimberly, Robert P, James, Judith A, Guthridge, Joel M, Harley, John B, Nath, Swapan K
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2010
Materias:
CD11b antigen
ITGAM antigen
Unclassified drug
Autoantibody
Arthritis
Article
Cohort analysis
Controlled study
Discoid rash
Disease association
Europe
Gene frequency
Genetic variability
Hematologic disease
Human
Hypothesis
Immunopathology
Inflammation
Kidney disease
Major clinical study
Mouth ulcer
Nephritis
Neurologic disease
Photosensitivity
Priority journal
Rash
Risk assessment
Systemic lupus erythematosus
Blood
Discoid lupus erythematosus
Female
Genetic predisposition
Genetics
Genotype
Immunology
Lupus erythematosus nephritis
Male
Autoantibodies
Gene Frequency
Genetic Predisposition to Disease
Humans
Lupus Nephritis
Systemic
human
Discoid
CD11b
ITGAM protein
Antigens
Lupus Erythematosus
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22389
https://doi.org/10.1136/ard.2009.120543

Internet

https://repository.urosario.edu.co/handle/10336/22389
https://doi.org/10.1136/ard.2009.120543

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