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Influence of Variations in CCL3L1 and CCR5 on Tuberculosis in a Northwestern Colombian Population

We investigated the association of polymorphisms in CCR5, the major human immunodeficiency virus (HIV)-1 coreceptor, and copy number of its potent ligand CCL3L1 with tuberculosis in 298 individuals from Colombia. The CCR5-HHD haplotype, a known genetic determinant of increased susceptibility to HIV-...

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Detalles Bibliográficos
Autores Principales: Mamtani M., Mummidi S., Ramsuran V., Pham M.-H., Maldonado R., Begum K., Valera M.S., Sanchez R., Castiblanco J., Kulkarni H., Ndung'u T., He W., Anaya, Juan-Manuel, Ahuja S.K.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2011
Materias:
CCL3L1 chemokine
Chemokine
Chemokine receptor CCR5
Macrophage inflammatory protein 1alpha
Membrane protein
Unclassified drug
Virus receptor
Acquired immune deficiency syndrome
Adult
Article
CCR5 gene
Colombia
Controlled study
DNA polymorphism
Female
Gene
Gene dosage
Genetic susceptibility
Genetic variability
Haplotype
Human
Human cell
Human immunodeficiency virus 1
Human immunodeficiency virus infection
Major clinical study
Male
Priority journal
Protein expression
Tuberculosis
Case-Control Studies
Gene Dosage
Haplotypes
Humans
Linkage Disequilibrium
Logistic Models
Middle Aged
CCR5
Genetic
CC
Chemokines
Polymorphism
Receptors
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22374
https://doi.org/10.1093/infdis/jir145

Internet

https://repository.urosario.edu.co/handle/10336/22374
https://doi.org/10.1093/infdis/jir145

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