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Preliminary Evaluation of the Safety and Immunogenicity of an Antimalarial Vaccine Candidate Modified Peptide (IMPIPS) Mixture in a Murine Model

Malaria continues being a high-impact disease regarding public health worldwide; the WHO report for malaria in 2018 estimated that 219 million cases occurred in 2017, mostly caused by the parasite Plasmodium falciparum. The disease cost the lives of more than 400,000 people, mainly in Africa. In spi...

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Detalles Bibliográficos
Autores Principales: Lambraño, Jennifer, Curtidor, Hernando, Avendaño, Catalina, Roa, Leonardo, Vanegas, Magnolia, Patarroyo, Manuel E, Díaz Arévalo, Diana, Patarroyo, Manuel A.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Hindawi Limited 2019
Materias:
Adjuvant
Immune protection inducing protein structure vaccine
Malaria vaccine
Plasmodium falciparum protein
Protozoal protein
Unclassified drug
Animal cell
Animal experiment
Article
Controlled study
Drug formulation
Drug safety
Drug synthesis
Erythrocyte
Female
Humoral immunity
Immunization
Immunogenicity
Immunological tolerance
In vitro study
In vivo study
Malaria falciparum
Male
Merozoite
Mouse
Nonhuman
Plasmodium falciparum
Protein structure
Repeated drug dose
Single drug dose
Vaccine immunogenicity
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22372
https://doi.org/10.1155/2019/3832513

Internet

https://repository.urosario.edu.co/handle/10336/22372
https://doi.org/10.1155/2019/3832513

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