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Genetics of non-syndromic childhood obesity and the use of high-throughput DNA sequencing technologies

Background Childhood obesity is a serious public health problem associated with the development of several chronic diseases, such as type 2 diabetes mellitus, dyslipidemia, and hypertension. The elevated prevalence of obesity is mostly due to inadequate diet and lifestyle, but it is also influenced...

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Detalles Bibliográficos
Autores Principales: da Fonseca, Ana Carolina Proença, Mastronardi, Claudio, Johar, Angad, Arcos-Burgos, Mauricio, Paz-Filho, Gilberto
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Elsevier Inc. 2017
Materias:
Leptin
Melanocortin
Dna
Appetite
Brain development
Childhood obesity
Chromosome analysis
Disease severity
Dna sequence
Endocrine disease
Gene mutation
Gene sequence
Genetic analysis
Genetic association
Genetic background
Genetic screening
Genetic variability
Genome analysis
Genome-wide association study
Heredity
High throughput sequencing
Human
Hypothalamus
Linkage analysis
Loss of function mutation
Medical decision making
Meta analysis (topic)
Microarray analysis
Monogenic disorder
Next generation sequencing
Nonhuman
Obesity
Priority journal
Rare variant association test
Review
Signal transduction
Whole exome sequencing
Biological model
Chemistry
Child
Genetic association study
Genetic linkage
Genetic polymorphism
Genetic predisposition
Genetics
Metabolism
Mutation
Procedures
Trends
Genetic association studies
Genetic predisposition to disease
Genetic testing
High-throughput nucleotide sequencing
Humans
Pediatric obesity
Dna sequencing
Gene
genetic
Models
Polymorphism
Acceso en línea:https://repository.urosario.edu.co/handle/10336/22326
https://doi.org/10.1016/j.jdiacomp.2017.04.026

Internet

https://repository.urosario.edu.co/handle/10336/22326
https://doi.org/10.1016/j.jdiacomp.2017.04.026

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