BMP15 mutations associated with primary ovarian insufficiency reduce expression, activity, or synergy with gdf9

Context: Bone morphogenetic protein (BMP)15 is an oocyte-specific growth factor, which, together with growth differentiation factor (GDF) 9, regulates folliculogenesis and ovulation rate. Multiple mutations in BMP15 have been identified in women with primary ovarian insufficiency (POI), supporting a...

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Detalles Bibliográficos
Autores Principales: Patiño, Liliana C., Walton, Kelly L., Mueller, Thomas D., Johnson, Katharine E., Stocker, William, Richani, Dulama, Agapiou, David, Gilchrist, Robert B., Laissue, Paul, Harrison, Craig A.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Endocrine Society 2017
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