Assessing Peptide Binding to MHC II: An Accurate Semiempirical Quantum Mechanics Based Proposal

Estimating peptide-major histocompatibility complex (pMHC) binding using structural computational methods has an impact on understanding overall immune function triggering adaptive immune responses in MHC class II molecules. We developed a strategy for optimizing pMHC structure interacting with wate...

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Detalles Bibliográficos
Autores Principales: Ortiz-Mahecha C.A., Bohórquez H.J., Agudelo W.A., Patarroyo M.A., Patarroyo M.E., Suárez C.F.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: American Chemical Society 2019
Acceso en línea: