Reference values for handgrip strength and their association with intrinsic capacity domains among older adults
Objective: The purposes of this study were three-fold: (i) to describe handgrip strength in older individuals aged ?60 years in Colombia; (ii) to identify sex-specific and age-specific muscle weakness cut-off points in older adults; and (iii) to determine the odds of adverse events for each of the i...
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Wiley Blackwell
2019
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| Acceso en línea: | https://repository.urosario.edu.co/handle/10336/22271 https://doi.org/10.1002/jcsm.12373 |
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ir-10336-222712022-05-02T12:37:18Z Reference values for handgrip strength and their association with intrinsic capacity domains among older adults Ramírez-Vélez, Robinson Correa Bautista, Jorge Enrique García?Hermoso, Antonio Cano, Carlos Alberto Izquierdo, Mikel Aged Alcohol consumption Article Body mass Clinical assessment Colombia Comorbidity Controlled study Cross-sectional study Demography Ethnic difference Female Grip strength Groups by age Hospitalization Human Locomotion Logistic regression analysis Major clinical study Male Muscle strength Muscle weakness Physical activity Priority journal Reference value Sarcopenia Smoking Social status Cognition Handgrip Locomotion Mental health Older adults Skeletal muscle Vitality Objective: The purposes of this study were three-fold: (i) to describe handgrip strength in older individuals aged ?60 years in Colombia; (ii) to identify sex-specific and age-specific muscle weakness cut-off points in older adults; and (iii) to determine the odds of adverse events for each of the intrinsic capacity domains for individuals with handgrip strength greater than the muscle weakness cut-off points, as compared with their weaker counterparts. Methods: A cross-sectional study was conducted in Colombia, among 5237 older adults aged ?60 years old (58.5% women, 70.5 ± 7.8 years), according to ‘SABE Survey 2015’. Handgrip strength data were obtained with a Takei dynamometer. Sociodemographic variables, five domains of intrinsic capacity (i.e. locomotion, vitality, cognition, psychological, and sensory), and medical conditions were assessed and analyzed. Adjustments variables were age, ethnicity, socio-economic status, urbanicity, body mass index, smoking status, alcohol intake, drug use, physical activity, and co-morbid chronic diseases. Sex-stratified analyses were conducted with logistic regression models. Results: Handgrip strength was greater among men than among women (26.7 ± 8.5 vs. 16.7 ± 5.7 kg, respectively, P less than 0.001) at all ages. Weak handgrip strength cut-off points ranged from 17.4 to 8.6 and from 10.1 to 4.9 in men and women, respectively. Overall, participants with optimal handgrip strength had better intrinsic capacity [in men, odds ratio (OR) = 0.62, 95% confidence interval (CI) 0.53 to 0.71; P less than 0.001; and in women, OR = 0.79, 95% CI 0.68 to 0.92; P = 0.002] than their weaker counterparts. Also, men with optimal handgrip strength had a lower risk of hospitalization (OR = 0.47, 95% CI 0.29 to 0.78; P = 0.004) than their weaker counterparts. Conclusions: This study is the first to describe handgrip strength values and cut-off points for muscle weakness among a nationally representative sample of Colombian older adults by age and sex. After categorizing older adults as weak or not weak based on the handgrip cut-off points, non-weakness was associated with a decreased odds of intrinsic capacity impairments. These cut-off points may be good candidates for clinical assessment of risks to physical and mental health in older Colombian adults. © 2019 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley and Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders 2019 2020-05-25T23:55:57Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 21905991 21906009 https://repository.urosario.edu.co/handle/10336/22271 https://doi.org/10.1002/jcsm.12373 eng info:eu-repo/semantics/openAccess application/pdf Wiley Blackwell instname:Universidad del Rosario |
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EdocUR - Universidad del Rosario |
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DSpace |
| language |
Inglés (English) |
| topic |
Aged Alcohol consumption Article Body mass Clinical assessment Colombia Comorbidity Controlled study Cross-sectional study Demography Ethnic difference Female Grip strength Groups by age Hospitalization Human Locomotion Logistic regression analysis Major clinical study Male Muscle strength Muscle weakness Physical activity Priority journal Reference value Sarcopenia Smoking Social status Cognition Handgrip Locomotion Mental health Older adults Skeletal muscle Vitality |
| spellingShingle |
Aged Alcohol consumption Article Body mass Clinical assessment Colombia Comorbidity Controlled study Cross-sectional study Demography Ethnic difference Female Grip strength Groups by age Hospitalization Human Locomotion Logistic regression analysis Major clinical study Male Muscle strength Muscle weakness Physical activity Priority journal Reference value Sarcopenia Smoking Social status Cognition Handgrip Locomotion Mental health Older adults Skeletal muscle Vitality Ramírez-Vélez, Robinson Correa Bautista, Jorge Enrique García?Hermoso, Antonio Cano, Carlos Alberto Izquierdo, Mikel Reference values for handgrip strength and their association with intrinsic capacity domains among older adults |
| description |
Objective: The purposes of this study were three-fold: (i) to describe handgrip strength in older individuals aged ?60 years in Colombia; (ii) to identify sex-specific and age-specific muscle weakness cut-off points in older adults; and (iii) to determine the odds of adverse events for each of the intrinsic capacity domains for individuals with handgrip strength greater than the muscle weakness cut-off points, as compared with their weaker counterparts. Methods: A cross-sectional study was conducted in Colombia, among 5237 older adults aged ?60 years old (58.5% women, 70.5 ± 7.8 years), according to ‘SABE Survey 2015’. Handgrip strength data were obtained with a Takei dynamometer. Sociodemographic variables, five domains of intrinsic capacity (i.e. locomotion, vitality, cognition, psychological, and sensory), and medical conditions were assessed and analyzed. Adjustments variables were age, ethnicity, socio-economic status, urbanicity, body mass index, smoking status, alcohol intake, drug use, physical activity, and co-morbid chronic diseases. Sex-stratified analyses were conducted with logistic regression models. Results: Handgrip strength was greater among men than among women (26.7 ± 8.5 vs. 16.7 ± 5.7 kg, respectively, P less than 0.001) at all ages. Weak handgrip strength cut-off points ranged from 17.4 to 8.6 and from 10.1 to 4.9 in men and women, respectively. Overall, participants with optimal handgrip strength had better intrinsic capacity [in men, odds ratio (OR) = 0.62, 95% confidence interval (CI) 0.53 to 0.71; P less than 0.001; and in women, OR = 0.79, 95% CI 0.68 to 0.92; P = 0.002] than their weaker counterparts. Also, men with optimal handgrip strength had a lower risk of hospitalization (OR = 0.47, 95% CI 0.29 to 0.78; P = 0.004) than their weaker counterparts. Conclusions: This study is the first to describe handgrip strength values and cut-off points for muscle weakness among a nationally representative sample of Colombian older adults by age and sex. After categorizing older adults as weak or not weak based on the handgrip cut-off points, non-weakness was associated with a decreased odds of intrinsic capacity impairments. These cut-off points may be good candidates for clinical assessment of risks to physical and mental health in older Colombian adults. © 2019 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley and Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders |
| format |
Artículo (Article) |
| author |
Ramírez-Vélez, Robinson Correa Bautista, Jorge Enrique García?Hermoso, Antonio Cano, Carlos Alberto Izquierdo, Mikel |
| author_facet |
Ramírez-Vélez, Robinson Correa Bautista, Jorge Enrique García?Hermoso, Antonio Cano, Carlos Alberto Izquierdo, Mikel |
| author_sort |
Ramírez-Vélez, Robinson |
| title |
Reference values for handgrip strength and their association with intrinsic capacity domains among older adults |
| title_short |
Reference values for handgrip strength and their association with intrinsic capacity domains among older adults |
| title_full |
Reference values for handgrip strength and their association with intrinsic capacity domains among older adults |
| title_fullStr |
Reference values for handgrip strength and their association with intrinsic capacity domains among older adults |
| title_full_unstemmed |
Reference values for handgrip strength and their association with intrinsic capacity domains among older adults |
| title_sort |
reference values for handgrip strength and their association with intrinsic capacity domains among older adults |
| publisher |
Wiley Blackwell |
| publishDate |
2019 |
| url |
https://repository.urosario.edu.co/handle/10336/22271 https://doi.org/10.1002/jcsm.12373 |
| _version_ |
1740172913526439936 |
| score |
12,131701 |