Imagen de Portada

Lupus risk variants in the PXK locus alter B-cell receptor internalization

Genome wide association studies have identified variants in PXK that confer risk for humoral autoimmune diseases, including systemic lupus erythematosus (SLE or lupus), rheumatoid arthritis and more recently systemic sclerosis. While PXK is involved in trafficking of epidermal growth factor Receptor...

Descripción completa

Detalles Bibliográficos
Autores Principales: Vaughn, Samuel E., Foley, Corinne, Lu, Xiaoming, Patel, Zubin H., Zoller, Erin E., Magnusen, Albert F., Williams, Adrienne H., Ziegler, Julie T., Comeau, Mary E., Marion, Miranda C., Tsao, Betty P., Jacob, Chaim O., Kamen, Diane L., Brown, Elizabeth E., Gikenson, Gary S., Alarcón, Graciela S., Reveille, John D., Anaya, Juan-Manuel, James, Judith A., Moser, Kathy L., Criswell, Lindsey A., Vilá, Luis M., Alarcon-Riquelme, Marta E., Petri, Michelle, Scofield, R. Hal, Kimberly, Robert P., Binjoo, Young, Choi, Jeongim, Bae, Sang-Cheol, Boackle, Susan A., Vyse, Timothy J., Guthridge, Joel M., Namjou, Bahram, Gaffney, Patrick M., Langefeld, Carl D., Kaufman, Kenneth M., Kelly, Jennifer A., Harley, Isaac T.W., Harley, John B., Kottyan, Leah C.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2014
Materias:
Enfermedades
lupus
PXK
fine-mapping
B cells
BCR
Acceso en línea:https://repository.urosario.edu.co/handle/10336/21786
https://doi.org/10.3389/fgene.2014.00450

Internet

https://repository.urosario.edu.co/handle/10336/21786
https://doi.org/10.3389/fgene.2014.00450

Ejemplares similares