Imagen de Portada

A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy

Background: Electrocardiographic measures of left ventricular hypertrophy (LVH) are used as predictors of cardiovascular risk. We combined linkage and association analyses to discover novel rare genetic variants involved in three such measures and two principal components derived from them. Methods:...

Descripción completa

Detalles Bibliográficos
Autores Principales: Tamar Silva, Claudia, Zorkoltseva, Irina V., Niemeijer, Maartje N., van den Berg, Marten E., Amin, Najaf, Demirkan, Ayşe, Leeuwen, Elisa van, Iglesias, Adriana I., Piñeros-Hernández, Laura B., Restrepo, Carlos M., Kors, Jan A., Kirichenko, Anatoly V., Willemsen, Rob, Oostra, Ben A., Stricker, Bruno H., Uitterlinden, André G., Axenovich, Tatiana I., Duijn, Cornelia M. van, Isaacs, Aaron
Otros Autores: Center for Research in Genetics and Genomics (CIGGUR)
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2018
Materias:
Chromosome 11
Chromosome 15
Dutchman
Exome Analysis
Gene
Gene Locus
Genetic Analysis
Genetic Association
Genetic Variability
Heart Left Ventricle Hypertrophy
Human
Limit Of Detection
Linkage Analysis
Major Clinical Study
Male
Map3K11 Gene
Microarray Analysis
Netherlands
Priority Journal
Whole Exome Sequencing
Cromosoma 11
Cromosoma 15
Enfermedades
Cardiomegalia
Enfermedades cardiovasculares
Adult
Article
Female
Middle Aged
Acceso en línea:https://repository.urosario.edu.co/handle/10336/20386
https://doi.org/10.1186/s12920-018-0339-9

Internet

https://repository.urosario.edu.co/handle/10336/20386
https://doi.org/10.1186/s12920-018-0339-9

Ejemplares similares