Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus

The review covers the functional and structural approach followed by our group for more than 34 years in the search for a methodology that allows the rational design of chemically synthesised vaccines. An analogy between Odysseus, the cunning hero of the epic poem Odyssey by Homer, and the elusive P...

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Autores Principales: Patarroyo, Manuel E., Patarroyo, Manuel A., Pabón, Laura, Curtidor, Hernando, Poloche, Luis A.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2015
Materias:
Acceso en línea:http://repository.urosario.edu.co/handle/10336/19014
id ir-10336-19014
recordtype dspace
spelling ir-10336-190142019-09-19T12:37:54Z Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus Patarroyo, Manuel E. Patarroyo, Manuel A. Pabón, Laura Curtidor, Hernando Poloche, Luis A. Impips Malaria Vaccine Modified Peptides Synthetic Peptides Enfermedades Malaria Vacuna Plasmodium Hla Dr1 Antigen Malaria Vaccine T Lymphocyte Receptor Malaria Vaccine Peptide Protozoal Protein Recombinant Vaccine Alpha Helix Amino Acid Sequence Antibody Response Antibody Titer Aotus Article Beta Sheet Conformational Transition Erythrocyte Genetic Trait Genetic Variability Human Humoral Immunity Hydrogen Bond Immune Protection Inducing Protein Structure Immune Response Immunogenetics Immunogenicity Immunological Silence Malaria Falciparum Nonhuman Plasmodium Falciparum Priority Journal Protein Conformation Protein Structure Chemistry Immunology Life Cycle Stage Malaria, Falciparum Metabolism Physiology Amino Acid Sequence Humans Life Cycle Stages Malaria Vaccines Malaria, Falciparum Peptides Plasmodium Falciparum Protein Conformation Protozoan Proteins Vaccines, Synthetic The review covers the functional and structural approach followed by our group for more than 34 years in the search for a methodology that allows the rational design of chemically synthesised vaccines. An analogy between Odysseus, the cunning hero of the epic poem Odyssey by Homer, and the elusive Plasmodium parasite has been made, to review our research group's main considerations when developing a rational methodology for designing second generation, modified peptide-based, minimal subunit, multi-antigen, multi-stage, chemically synthesised vaccines against Plasmodium falciparum malaria. © 2015 Elsevier Ltd. 2015 2019-02-05T19:54:55Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ISSN 0264-410X http://repository.urosario.edu.co/handle/10336/19014 eng info:eu-repo/semantics/openAccess application/pdf Homer, (1946) The Odyssey, , [Transl. by E.V. Rieu], Penguin Group, London, England
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic Impips
Malaria Vaccine
Modified Peptides
Synthetic Peptides
Enfermedades
Malaria
Vacuna
Plasmodium
Hla Dr1 Antigen
Malaria Vaccine
T Lymphocyte Receptor
Malaria Vaccine
Peptide
Protozoal Protein
Recombinant Vaccine
Alpha Helix
Amino Acid Sequence
Antibody Response
Antibody Titer
Aotus
Article
Beta Sheet
Conformational Transition
Erythrocyte
Genetic Trait
Genetic Variability
Human
Humoral Immunity
Hydrogen Bond
Immune Protection Inducing Protein Structure
Immune Response
Immunogenetics
Immunogenicity
Immunological Silence
Malaria Falciparum
Nonhuman
Plasmodium Falciparum
Priority Journal
Protein Conformation
Protein Structure
Chemistry
Immunology
Life Cycle Stage
Malaria, Falciparum
Metabolism
Physiology
Amino Acid Sequence
Humans
Life Cycle Stages
Malaria Vaccines
Malaria, Falciparum
Peptides
Plasmodium Falciparum
Protein Conformation
Protozoan Proteins
Vaccines, Synthetic
spellingShingle Impips
Malaria Vaccine
Modified Peptides
Synthetic Peptides
Enfermedades
Malaria
Vacuna
Plasmodium
Hla Dr1 Antigen
Malaria Vaccine
T Lymphocyte Receptor
Malaria Vaccine
Peptide
Protozoal Protein
Recombinant Vaccine
Alpha Helix
Amino Acid Sequence
Antibody Response
Antibody Titer
Aotus
Article
Beta Sheet
Conformational Transition
Erythrocyte
Genetic Trait
Genetic Variability
Human
Humoral Immunity
Hydrogen Bond
Immune Protection Inducing Protein Structure
Immune Response
Immunogenetics
Immunogenicity
Immunological Silence
Malaria Falciparum
Nonhuman
Plasmodium Falciparum
Priority Journal
Protein Conformation
Protein Structure
Chemistry
Immunology
Life Cycle Stage
Malaria, Falciparum
Metabolism
Physiology
Amino Acid Sequence
Humans
Life Cycle Stages
Malaria Vaccines
Malaria, Falciparum
Peptides
Plasmodium Falciparum
Protein Conformation
Protozoan Proteins
Vaccines, Synthetic
Patarroyo, Manuel E.
Patarroyo, Manuel A.
Pabón, Laura
Curtidor, Hernando
Poloche, Luis A.
Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
description The review covers the functional and structural approach followed by our group for more than 34 years in the search for a methodology that allows the rational design of chemically synthesised vaccines. An analogy between Odysseus, the cunning hero of the epic poem Odyssey by Homer, and the elusive Plasmodium parasite has been made, to review our research group's main considerations when developing a rational methodology for designing second generation, modified peptide-based, minimal subunit, multi-antigen, multi-stage, chemically synthesised vaccines against Plasmodium falciparum malaria. © 2015 Elsevier Ltd.
format Artículo (Article)
author Patarroyo, Manuel E.
Patarroyo, Manuel A.
Pabón, Laura
Curtidor, Hernando
Poloche, Luis A.
author_facet Patarroyo, Manuel E.
Patarroyo, Manuel A.
Pabón, Laura
Curtidor, Hernando
Poloche, Luis A.
author_sort Patarroyo, Manuel E.
title Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
title_short Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
title_full Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
title_fullStr Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
title_full_unstemmed Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
title_sort immune protection-inducing protein structures (impips) against malaria : the weapons needed for beating odysseus
publishDate 2015
url http://repository.urosario.edu.co/handle/10336/19014
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score 10,684066