Inflammatory myofibroblastic tumor presenting as paraneoplastic pemphigus in a 7-year-old girl
Introduction: Paraneoplastic pemphigus is an autoimmune disease associated with an underlying tumor. Several cases have been reported as unusual pemphigus vulgaris, erythema multiforme, or paraneoplastic bullous disease,1 but the incidence of the condition is unknown.2 Response to treatment is gener...
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| Formato: | Artículo (Article) |
| Lenguaje: | Inglés (English) |
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2016
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| Acceso en línea: | http://repository.urosario.edu.co/handle/10336/18971 |
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ir-10336-189712022-05-02T12:37:22Z Inflammatory myofibroblastic tumor presenting as paraneoplastic pemphigus in a 7-year-old girl Halpert, Evelyne Figueroa, Juan Luis Rojas, Armando Ortiz, Clara Ines Chaparro, Daniela Galindo, Marcela Lammoglia, Juan Javier Rumie, Carolina Olmos, Carlos Myofibroblastic Tumor Paraneoplastic Syndromes Pediatrics Pemphigus Vulgaris Enfermedades Enfermedades autoinmunes Eritema multiforme Pénfigo Azathioprine Methylprednisolone Oxacillin Prednisone Rituximab Thalidomide Article Case Report Cataract Child Colombia Cushing Syndrome Depression Female Hospitalization Human Immunofluorescence Medical History Mouth Ulcer Myopathy Paraneoplastic Pemphigus Pemphigus Vulgaris Plasma Cell Granuloma Priority Journal Psychotherapy School Child Skin Biopsy Skin Defect Skin Infection Introduction: Paraneoplastic pemphigus is an autoimmune disease associated with an underlying tumor. Several cases have been reported as unusual pemphigus vulgaris, erythema multiforme, or paraneoplastic bullous disease,1 but the incidence of the condition is unknown.2 Response to treatment is generally poor, with significant morbidity and mortality. This condition is clinically characterized by severe mucositis and polymorphic blistering skin eruptions, and histologically by acantholysis, keratinocyte necrosis, and interface dermatitis.3 Immunoprecipitation and immunoblot testing detect autoantibodies against desmosomal polypeptides.4 We describe a case of paraneoplastic pemphigus associated with an abdominal inflammatory myofibroblastic tumor in a 7-year-old girl. 2016 2019-01-31T14:46:18Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ISSN 2352-5126 http://repository.urosario.edu.co/handle/10336/18971 eng info:eu-repo/semantics/openAccess application/pdf instname:Universidad del Rosario |
| institution |
EdocUR - Universidad del Rosario |
| collection |
DSpace |
| language |
Inglés (English) |
| topic |
Myofibroblastic Tumor Paraneoplastic Syndromes Pediatrics Pemphigus Vulgaris Enfermedades Enfermedades autoinmunes Eritema multiforme Pénfigo Azathioprine Methylprednisolone Oxacillin Prednisone Rituximab Thalidomide Article Case Report Cataract Child Colombia Cushing Syndrome Depression Female Hospitalization Human Immunofluorescence Medical History Mouth Ulcer Myopathy Paraneoplastic Pemphigus Pemphigus Vulgaris Plasma Cell Granuloma Priority Journal Psychotherapy School Child Skin Biopsy Skin Defect Skin Infection |
| spellingShingle |
Myofibroblastic Tumor Paraneoplastic Syndromes Pediatrics Pemphigus Vulgaris Enfermedades Enfermedades autoinmunes Eritema multiforme Pénfigo Azathioprine Methylprednisolone Oxacillin Prednisone Rituximab Thalidomide Article Case Report Cataract Child Colombia Cushing Syndrome Depression Female Hospitalization Human Immunofluorescence Medical History Mouth Ulcer Myopathy Paraneoplastic Pemphigus Pemphigus Vulgaris Plasma Cell Granuloma Priority Journal Psychotherapy School Child Skin Biopsy Skin Defect Skin Infection Halpert, Evelyne Figueroa, Juan Luis Rojas, Armando Ortiz, Clara Ines Chaparro, Daniela Galindo, Marcela Lammoglia, Juan Javier Rumie, Carolina Olmos, Carlos Inflammatory myofibroblastic tumor presenting as paraneoplastic pemphigus in a 7-year-old girl |
| description |
Introduction: Paraneoplastic pemphigus is an autoimmune disease associated with an underlying tumor. Several cases have been reported as unusual pemphigus vulgaris, erythema multiforme, or paraneoplastic bullous disease,1 but the incidence of the condition is unknown.2 Response to treatment is generally poor, with significant morbidity and mortality. This condition is clinically characterized by severe mucositis and polymorphic blistering skin eruptions, and histologically by acantholysis, keratinocyte necrosis, and interface dermatitis.3 Immunoprecipitation and immunoblot testing detect autoantibodies against desmosomal polypeptides.4 We describe a case of paraneoplastic pemphigus associated with an abdominal inflammatory myofibroblastic tumor in a 7-year-old girl. |
| format |
Artículo (Article) |
| author |
Halpert, Evelyne Figueroa, Juan Luis Rojas, Armando Ortiz, Clara Ines Chaparro, Daniela Galindo, Marcela Lammoglia, Juan Javier Rumie, Carolina Olmos, Carlos |
| author_facet |
Halpert, Evelyne Figueroa, Juan Luis Rojas, Armando Ortiz, Clara Ines Chaparro, Daniela Galindo, Marcela Lammoglia, Juan Javier Rumie, Carolina Olmos, Carlos |
| author_sort |
Halpert, Evelyne |
| title |
Inflammatory myofibroblastic tumor presenting as paraneoplastic pemphigus in a 7-year-old girl |
| title_short |
Inflammatory myofibroblastic tumor presenting as paraneoplastic pemphigus in a 7-year-old girl |
| title_full |
Inflammatory myofibroblastic tumor presenting as paraneoplastic pemphigus in a 7-year-old girl |
| title_fullStr |
Inflammatory myofibroblastic tumor presenting as paraneoplastic pemphigus in a 7-year-old girl |
| title_full_unstemmed |
Inflammatory myofibroblastic tumor presenting as paraneoplastic pemphigus in a 7-year-old girl |
| title_sort |
inflammatory myofibroblastic tumor presenting as paraneoplastic pemphigus in a 7-year-old girl |
| publishDate |
2016 |
| url |
http://repository.urosario.edu.co/handle/10336/18971 |
| _version_ |
1740172471275880448 |
| score |
12,131701 |