Existencias: Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study

Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study

Systemic lupus erythematosus (SLE) is a chronic heterogeneous autoimmune disorder characterized by the loss of tolerance to self-antigens and dysregulated interferon responses. The etiology of SLE is complex, involving both heritable and environmental factors. Candidate-gene studies and genome-wide...

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Autores Principales:	Lessard, Christopher J., Adrianto, Indra, Ice, John A., Wiley, Graham B., Kelly, Jennifer A., Glenn, Stuart B., Adler, Adam J., Li, He, Rasmussen, Astrid, Williams, Adrienne H., Ziegler, Julie, Comeau, Mary, Marion, Miranda, Wakeland, Benjamin E., Liang, Chaoying, Ramos, Paula S., Grundahl, Kiely M., Gallant, Caroline J., Alarcón-Riquelme, Marta E., Alarcón, Graciela S., Anaya, Juan-Manuel, Bae, Sang-Cheol, Boackle, Susan, Brown, Elizabeth E., Chang, Deh-Ming, Cho, Soo-Kyung, Criswel, Lindsey A., Edberg, Jeffrey C., Freedman, Barry I., Gilkeson, Gary S., Jacob, Chaim O., James, Judith A., Kamen, Diane L., Kimberly, Robert P., Kim, Jae-Hoon, Martin, Javier, Merrill, Joan T., Niewold, Timothy B., Park, So-Yeon, Petri, Michelle A., Pons-Estel, Bernardo A., Ramsey-Goldman, Rosalind, Reveille, John D., Scofield, Robert H., Song, Yeong Wook, Stevens, Anne M., Tsao, Betty P., Vila, Luis M., Vyse, Timothy J., Yu, Chack-Yung, Guthridge, Joel M., Kaufman, Kenneth M., Harley, John B., Wakeland, Edward K., Langefeld, Carl D., Gaffney, Patrick M., Montgomery, Courtney G., Moser, Kathy L.
Formato:	Artículo (Article)
Lenguaje:	Inglés (English)
Publicado:	2012
Materias:	Autoantigen Ikaros Transcription Factor Interferon Interferon Consensus Sequence Binding Protein Membrane Protein Protein Ikzf3 Transmembrane Protein 39A Unclassified Drug Zona Pellucida Binding Protein 2 Adamtsl1 Gene African American American Indian Article Asian C1Orf64 Gene Cadm2 Gene Cfhr1 Gene Chromosome 17Q Controlled Study Environmental Factor Ethnicity European American Fam19A2 Gene Gene Gene Identification Gene Locus Gene Mapping Gene Sequence Genetic Association Genetic Risk Genetic Susceptibility Genetic Variability Genome Analysis Genotype Haplotype Heritability High Risk Population Hispanic Human Ikzf3 Gene Il12A Gene Immune Response Immunological Tolerance Immunoregulation Irf8 Gene Loc6392 Gene Lpp Gene Major Clinical Study Or8D4 Gene Priority Journal Single Nucleotide Polymorphism Slu7 Gene Stxbp6 Gene Systemic Lupus Erythematosus Tmem39A Gene Zpbp2 Gene African Continental Ancestry Group Asian Continental Ancestry Group Chromosome Mapping Egg Proteins European Continental Ancestry Group Female Genetic Predisposition To Disease Haplotypes Hispanic Americans Humans Indians, North American Interferon Regulatory Factors Lupus Erythematosus, Systemic Male Membrane Proteins Polymorphism, Single Nucleotide Sequence Analysis, Dna Lupus eritematoso sistémico Genética Patología
Acceso en línea:	http://repository.urosario.edu.co/handle/10336/18736

Internet

http://repository.urosario.edu.co/handle/10336/18736

Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study

Internet

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