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Development of peptide-based lineage-specific serology for chronic Chagas disease : Geographical and clinical distribution of epitope recognition

Background:Chagas disease, caused by infection with the protozoan Trypanosoma cruzi, remains a serious public health issue in Latin America. Genetically diverse, the species is sub-divided into six lineages, known as TcI-TcVI, which have disparate geographical and ecological distributions. TcII, TcV...

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Detalles Bibliográficos
Autores Principales: Bhattacharyya, Tapan, Falconar, Andrew K., Luquetti, Alejandro O., Costales, Jaime A., Grijalva, Mario J., Lewis, Michael D., Messenger, Louisa A., Tran, Trang T., Ramírez, Juan David, Guhl, Felipe, Carrasco, Hernan J., Diosque, Patricio, Garcia, Lineth, Litvinov, Sergey V., Miles, Michael A.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2014
Materias:
Enfermedad de Chagas
Trypanosomiasis
Cardiomiopatía Chagásica
Antibody
Protozoan
Trypanosoma
Avidin
Biotin
Glycine
Macrogol
Parasite Antigen
Synthetic Peptide
Epitope
Peptide
Protozoon Antibody
Trypomastigote Small Surface Antigen
Variant Surface Glycoprotein
Algorithm
Animal Experiment
Antibody Response
Antibody Specificity
Antigen Recognition
Brazil
Cell Lineage
Cell Lysate
Chagas Disease
Chronic Disease
Comparative Study
Controlled Study
Ecg Abnormality
Enzyme Linked Immunosorbent Assay
Genotyping Technique
Geographic Distribution
Human
Immunogenicity
Major Clinical Study
Mouse
Nonhuman
Nucleotide Sequence
Parasite Identification
Peptide Synthesis
Polymerase Chain Reaction
Serology
South America
Trypanosoma Cruzi
Amino Acid Sequence
Animal
Biology
Blood
Chemistry
Classification
Immunology
Molecular Genetics
Parasitology
Procedures
Serotyping
Triatoma
Algorithms
Animals
Antibodies
Antigens
Computational Biology
Epitopes
Mice
Molecular Sequence Data
Peptides
Variant Surface
Glycoproteins
Acceso en línea:http://repository.urosario.edu.co/handle/10336/18724
https://doi.org/10.1371/journal.pntd.0002892

Internet

http://repository.urosario.edu.co/handle/10336/18724
https://doi.org/10.1371/journal.pntd.0002892

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