Existencias: Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1

Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1

Non-coding RNAs are a complex class of nucleic acids, with growing evidence supporting regulatory roles in gene expression. Here we identify a non-coding RNA located head-to-head with the gene encoding the Glioma-associated oncogene 1 (GLI1), a transcriptional effector of multiple cancer-associated...

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Detalles Bibliográficos
Autores Principales:	Villegas, Victoria E., Rahman, Mohammed Ferdous-Ur, Fernandez-Barrena, Maite G., Diao, Yumei, Liapi, Eleni, Sonkoly, Eniko, Stahle, Mona, Pivarcsi, Andor, Annaratone, Laura, Sapino, Anna, Ramírez-Clavijo, Sandra, Burglin, Thomas R., Shimokawa, Takashi, Ramachandran, Saraswathi, Kapranov, Philipp, Fernandez-Zapico, Martin E., Zaphiropoulos, Peter G.
Formato:	Artículo (Article)
Lenguaje:	Inglés (English)
Publicado:	2014
Materias:	Cancer Chromatin Gene Expression Gli1 Non-Coding Rna Transcription Cromatina Expresión genética Cáncer Complementary Rna Protein Patched 1 Protein Patched 2 Rna Polymerase Ii Small Interfering Rna Sonic Hedgehog Protein Transcription Factor Gli1 Untranslated Rna Gli Protein Oncoprotein Transactivator Protein Transforming Growth Factor Beta Article Breast Cancer Breast Fibroadenoma Cancer Cell Cell Proliferation Chromatin Assembly And Disassembly Chromatin Immunoprecipitation Chromatin Structure Chromosome 21Q Comparative Study Controlled Study Down Regulation Exon Gene Silencing Genetic Transfection Human Human Tissue Negative Feedback Nucleotide Sequence Oncogene Polyadenylation Priority Journal Promoter Region Regulatory Mechanism Rna Sequence Signal Transduction Transcription Initiation Site Tumor Growth Upregulation Gene Expression Regulation Genetics Metabolism Neoplasm Pathology Transcription Initiation Tumor Cell Line Genetic Transcription Human Cell Erinaceidae Cell Line, Tumor Gene Expression Regulation, Neoplastic Hedgehog Proteins Humans Neoplasms Oncogene Proteins Rna, Untranslated Trans-Activators Transcriptional Activation
Acceso en línea:	http://repository.urosario.edu.co/handle/10336/18719

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http://repository.urosario.edu.co/handle/10336/18719

Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1

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