Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1

Non-coding RNAs are a complex class of nucleic acids, with growing evidence supporting regulatory roles in gene expression. Here we identify a non-coding RNA located head-to-head with the gene encoding the Glioma-associated oncogene 1 (GLI1), a transcriptional effector of multiple cancer-associated...

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Detalles Bibliográficos
Autores Principales: Villegas, Victoria E., Rahman, Mohammed Ferdous-Ur, Fernandez-Barrena, Maite G., Diao, Yumei, Liapi, Eleni, Sonkoly, Eniko, Stahle, Mona, Pivarcsi, Andor, Annaratone, Laura, Sapino, Anna, Ramírez-Clavijo, Sandra, Burglin, Thomas R., Shimokawa, Takashi, Ramachandran, Saraswathi, Kapranov, Philipp, Fernandez-Zapico, Martin E., Zaphiropoulos, Peter G.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2014
Materias:
Acceso en línea:http://repository.urosario.edu.co/handle/10336/18719