Recombinant vaccines of a CD4+ T-cell epitope promote efficient control of Paracoccidioides brasiliensis burden by restraining primary organ infection

Paracoccidioidomycosis (PCM) is an infectious disease endemic to South America, caused by the thermally dimorphic fungi Paracoccidioides. Currently, there is no effective human vaccine that can be used in prophylactic or therapeutic regimes. We tested the hypothesis that the immunogenicity of the im...

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Detalles Bibliográficos
Autores Principales: Alves Santos, Julliana Ribeiro, Assuncão Holanda, Rodrigo, Muñoz, J.E., Santos Dias, Lucas, Roque Silva, Leandro Buffoni, Pagliari, Sthefany, Leandro, Érica, Vieira, Marciano, Alves Paixão, Tatiane, Pelleschi Taborda, Carlos, Assis Santos, Daniel, Bruña-Romero, Oscar
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2017
Materias:
Acceso en línea:http://repository.urosario.edu.co/handle/10336/18682
https://doi.org/10.1371/journal.pntd.0005927