Efectividad de la vacuna Acelular Antipertusis en el embarazo y su protección al recién nacido : revisión sistemática

Se trata de un revisión sistemática de la literatura para evaluar la evidencia sobre la efectividad de la vacuna acelular antipertussis mediante la medición de los niveles de anticuerpos contra B. pertussis en el neonato e infante menor de dos meses, reflejando el paso transplacentario de anticuerpo...

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Autor Principal: Rodriguez Basto, Lucia Marcela
Otros Autores: Alvarez, Martha Isabel
Formato: Tesis de maestría (Master Thesis)
Lenguaje:Español (Spanish)
Publicado: Universidad del Rosario 2017
Materias:
Acceso en línea:http://repository.urosario.edu.co/handle/10336/14136
id ir-10336-14136
recordtype dspace
institution EdocUR - Universidad del Rosario
collection DSpace
language Español (Spanish)
topic Efectividad
Inmunización pasiva
Vacuna acelular antipertusis
Recién nacido
Effectiveness
Passive immunization
Anti-pertussis
Acellular vaccines
Newborn
Vacunas contra Difteria, Tétanos y Tos Ferina Acelular Quitar
Anticuerpos
Recién Nacido
spellingShingle Efectividad
Inmunización pasiva
Vacuna acelular antipertusis
Recién nacido
Effectiveness
Passive immunization
Anti-pertussis
Acellular vaccines
Newborn
Vacunas contra Difteria, Tétanos y Tos Ferina Acelular Quitar
Anticuerpos
Recién Nacido
Rodriguez Basto, Lucia Marcela
Efectividad de la vacuna Acelular Antipertusis en el embarazo y su protección al recién nacido : revisión sistemática
description Se trata de un revisión sistemática de la literatura para evaluar la evidencia sobre la efectividad de la vacuna acelular antipertussis mediante la medición de los niveles de anticuerpos contra B. pertussis en el neonato e infante menor de dos meses, reflejando el paso transplacentario de anticuerpos maternos contra la tosferina.
author2 Alvarez, Martha Isabel
author_facet Alvarez, Martha Isabel
Rodriguez Basto, Lucia Marcela
format Tesis de maestría (Master Thesis)
author Rodriguez Basto, Lucia Marcela
author_sort Rodriguez Basto, Lucia Marcela
title Efectividad de la vacuna Acelular Antipertusis en el embarazo y su protección al recién nacido : revisión sistemática
title_short Efectividad de la vacuna Acelular Antipertusis en el embarazo y su protección al recién nacido : revisión sistemática
title_full Efectividad de la vacuna Acelular Antipertusis en el embarazo y su protección al recién nacido : revisión sistemática
title_fullStr Efectividad de la vacuna Acelular Antipertusis en el embarazo y su protección al recién nacido : revisión sistemática
title_full_unstemmed Efectividad de la vacuna Acelular Antipertusis en el embarazo y su protección al recién nacido : revisión sistemática
title_sort efectividad de la vacuna acelular antipertusis en el embarazo y su protección al recién nacido : revisión sistemática
publisher Universidad del Rosario
publishDate 2017
url http://repository.urosario.edu.co/handle/10336/14136
_version_ 1694382531927867392
spelling ir-10336-141362021-03-01T19:22:57Z Efectividad de la vacuna Acelular Antipertusis en el embarazo y su protección al recién nacido : revisión sistemática Rodriguez Basto, Lucia Marcela Alvarez, Martha Isabel Villaveces, Mariana Efectividad Inmunización pasiva Vacuna acelular antipertusis Recién nacido Effectiveness Passive immunization Anti-pertussis Acellular vaccines Newborn Vacunas contra Difteria, Tétanos y Tos Ferina Acelular Quitar Anticuerpos Recién Nacido Se trata de un revisión sistemática de la literatura para evaluar la evidencia sobre la efectividad de la vacuna acelular antipertussis mediante la medición de los niveles de anticuerpos contra B. pertussis en el neonato e infante menor de dos meses, reflejando el paso transplacentario de anticuerpos maternos contra la tosferina. Backround: With the worldwide resurgence of pertusiss in 2011, and letal infection in neonates and infants under two months of age, new vaccination strategies have been sought to reduce infant mortality and prevent fatal cases of Bordetella pertussis, including vaccination of pregnant women, based on the effective passage of maternal antibodies to the neonate. Methods: Systematic review of articles literature to evaluate the effectiveness of vertical transference of antibodies to neonates with the application of the acellular antipertussis vaccine to provide protection to the newborn and the infant under 2 months – old. Results: After a rigorous search, 18 articles were included for analysis and extraction of evidence. The effectiveness of the Tdap vaccine exceeded 90% in neonates, taking into account the levels of antibodies in the same. The reactogenicity, in generall was low. Discussion: The vaccine against pertussis in pregnant women appears to be a safe, effective and accepted strategy to protect the newborn during the first weeks of life. For this reason it has been recommended for all pregnant women dduring each pregnancy, a measure adopted in different countries of Europe and in America including our country. Conclusion: Available evidence suggests that the Tdap vaccine may be recommended in pregnant women between week 27-36 of gestation, a period in which there is a greater transplacental passage of antibodies against pertussis. Accelerating Tdap in pregnant women is an effective strategy with no side effects and low cost.. Key words: Effectiveness, passive immunization, anti-pertussis acellular vaccines, newborn. 2017-11-24 2017-12-07T17:42:36Z info:eu-repo/semantics/masterThesis info:eu-repo/semantics/acceptedVersion http://repository.urosario.edu.co/handle/10336/14136 spa info:eu-repo/semantics/openAccess application/pdf Universidad del Rosario Especialización en Pediatría Facultad de medicina reponame:Repositorio Institucional EdocUR instname:Universidad del Rosario Zhang L, Prietsch SO, Axelsson I, Halperin S a. Acellular vaccines for preventing whooping cough in children. Cochrane Database Syst Rev. 2011;(1):CD001478. World Health Organization. Laboratory manual for the diagnosis of whooping cough caused by Bordetella pertussis/ Bordetella parapertussis. 2007;04/14. Vacunación de las embarazadas frente a la tos ferina en la comunidad de Valencia. De, Dirección General de Salud Pública Servicio de Salud Infantil y de la Mujer Servicio , Vigilancia y Control Epidemiológico. 2012;24. 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