The effector of hedgehog signaling, the transcription factor GLI1: novel regulatory mechanisms and role in tamoxifen treatment

In Chapter I, we describe the characterization of an RNA transcript from the antisense strand of the GLI1 gene, termed GLI1AS, with no potential to code for a long protein, which acts as a negative regulator of GLI1 expression. We provide evidence for capping and polyadenylation of this antisense RN...

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Detalles Bibliográficos
Autor Principal: Villegas, Victoria E.
Otros Autores: Zaphiropoulos, Peter
Formato: Tesis de doctorado (Doctoral Thesis)
Lenguaje:Español (Spanish)
Publicado: Universidad del Rosario 2017
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