Protección miocárdica con custodiol y trastornos de la osmolalidad

En análisis retrospectivo evaluamos 91 pacientes llevados a cirugía cardiaca entre 2013 y 2014 en la Fundación Cardioinfantil, en quienes se administro Custodiol, analizando los niveles de sodio y osmolalidad plasmática efectiva antes, durante y después del procedimiento quirúrgico. Nosotros evalu...

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Detalles Bibliográficos
Autor Principal: Valero Garzón, Wilmer
Otros Autores: Montes Romero, Felix Ramon
Formato: Tesis de maestría (Master Thesis)
Lenguaje:Español (Spanish)
Publicado: Universidad del Rosario 2015
Materias:
Acceso en línea:http://repository.urosario.edu.co/handle/10336/10700
id ir-10336-10700
recordtype dspace
institution EdocUR - Universidad del Rosario
collection DSpace
language Español (Spanish)
topic Hiponatremia
Custodiol
Bypass cardiopulmonar
Cirugía cardiaca
Varias ramas de la medicina, Cirugía
Anestesiología
Cirugía cardiaca
Anestesia en cardiología
Hyponatremia
Custodiol
Cardiopulmonary bypass
Cardiac surgery
Cirugía torácica
Anestésicos
spellingShingle Hiponatremia
Custodiol
Bypass cardiopulmonar
Cirugía cardiaca
Varias ramas de la medicina, Cirugía
Anestesiología
Cirugía cardiaca
Anestesia en cardiología
Hyponatremia
Custodiol
Cardiopulmonary bypass
Cardiac surgery
Cirugía torácica
Anestésicos
Valero Garzón, Wilmer
Protección miocárdica con custodiol y trastornos de la osmolalidad
description En análisis retrospectivo evaluamos 91 pacientes llevados a cirugía cardiaca entre 2013 y 2014 en la Fundación Cardioinfantil, en quienes se administro Custodiol, analizando los niveles de sodio y osmolalidad plasmática efectiva antes, durante y después del procedimiento quirúrgico. Nosotros evaluamos la relación entre administración de Custodiol y cambios en el sodio y osmolalidad plasmática del paciente llevado a cirugía cardiaca.
author2 Montes Romero, Felix Ramon
author_facet Montes Romero, Felix Ramon
Valero Garzón, Wilmer
format Tesis de maestría (Master Thesis)
author Valero Garzón, Wilmer
author_sort Valero Garzón, Wilmer
title Protección miocárdica con custodiol y trastornos de la osmolalidad
title_short Protección miocárdica con custodiol y trastornos de la osmolalidad
title_full Protección miocárdica con custodiol y trastornos de la osmolalidad
title_fullStr Protección miocárdica con custodiol y trastornos de la osmolalidad
title_full_unstemmed Protección miocárdica con custodiol y trastornos de la osmolalidad
title_sort protección miocárdica con custodiol y trastornos de la osmolalidad
publisher Universidad del Rosario
publishDate 2015
url http://repository.urosario.edu.co/handle/10336/10700
_version_ 1694382529384022016
spelling ir-10336-107002021-03-01T19:22:50Z Protección miocárdica con custodiol y trastornos de la osmolalidad Valero Garzón, Wilmer Montes Romero, Felix Ramon Hiponatremia Custodiol Bypass cardiopulmonar Cirugía cardiaca Varias ramas de la medicina, Cirugía Anestesiología Cirugía cardiaca Anestesia en cardiología Hyponatremia Custodiol Cardiopulmonary bypass Cardiac surgery Cirugía torácica Anestésicos En análisis retrospectivo evaluamos 91 pacientes llevados a cirugía cardiaca entre 2013 y 2014 en la Fundación Cardioinfantil, en quienes se administro Custodiol, analizando los niveles de sodio y osmolalidad plasmática efectiva antes, durante y después del procedimiento quirúrgico. Nosotros evaluamos la relación entre administración de Custodiol y cambios en el sodio y osmolalidad plasmática del paciente llevado a cirugía cardiaca. Introduction: Hyponatremia and osmolality disorders have been identified as independent predictors of increased morbidity, mortality and length of hospital stay in patients after cardiac surgery. Administration of Custodiol for myocardial protection may alter serum sodium levels and thereby alter the effective plasma osmolality. We evaluated the relationship between administration of Custodiol, and the fluctuation of sodium concentration and plasma osmolality in heart surgery patients. Methods: In this retrospective analysis we reviewed 91 patients who underwent cardiac surgery from 2013 to 2014 in the Fundación Cardioinfantil. Custodiol was administered to all patients. Sodium levels were analyzed and effective plasma osmolality was calculated before, during and after the surgical procedure. Results: All patients were normonatremic at start of surgery. 93.47% of patients developed hyponatremia after administering Custodiol with a significant decrease in mean serum sodium 12.43 mEq/l (P <0.001). Upon completion of the surgical procedure average effective plasma osmolality was 278.47 ± 8.11 mOsm/L (median=278) and the mean serum sodium was 135.35 ± 4.18 mEq / L (median=135). Presenting a significant difference before and after cardiopulmonary bypass (p<0.001, repeated measures ANOVA Friedman, CM). Conclusions: The use of Custodiol produces a significant decrease on the effective plasmatic osmolality and serum sodium. However the median of effective plasmatic osmolality and serum sodium are in normal range at the end of the cardiac surgery. 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